567570 Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp. - CAS 22189-32-8 - Calbiochem

567570
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Overview

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Key Spec Table

Empirical FormulaCAS #
C₁₄H₂₄N₂O₇ · 2HCl · 5H₂O22189-32-8

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567570-10GMCN
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      Glass bottle 10 gm
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      Description
      OverviewA broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire’s disease) kinase and expressed in E. coli. Potency: ≥500 µg/mg.
      Catalogue Number567570
      Brand Family Calbiochem®
      References
      ReferencesThompson, P.R., et al. 1998. J. Biol. Chem. 273, 14788.
      Noah, J., and Wollenzien, P. 1997. Nucleic Acids Symp. Ser. 36, 178.
      Suter, T.M., et al. 1997. Antimicrob. Agents Chemother. 41, 1385.
      Thom, G., and Prescott, C.D. 1997. Bioorg. Med. Chem. 5, 1081.
      Product Information
      CAS number22189-32-8
      FormWhite to off-white solid
      Hill FormulaC₁₄H₂₄N₂O₇ · 2HCl · 5H₂O
      Chemical formulaC₁₄H₂₄N₂O₇ · 2HCl · 5H₂O
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationSpectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp., CAS 22189-32-8, is a broad spectrum aminoglycoside antibiotic that blocks protein synthesis by binding to the 30S ribosomal subunit.
      Biological Information
      Primary TargetFootprint studies indicate that spectinomycin exerts regional effects on ribosomal structure
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSWG7400000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp. - CAS 22189-32-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      567570

      References

      Reference overview
      Thompson, P.R., et al. 1998. J. Biol. Chem. 273, 14788.
      Noah, J., and Wollenzien, P. 1997. Nucleic Acids Symp. Ser. 36, 178.
      Suter, T.M., et al. 1997. Antimicrob. Agents Chemother. 41, 1385.
      Thom, G., and Prescott, C.D. 1997. Bioorg. Med. Chem. 5, 1081.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-May-2008 RFH
      DescriptionA broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire's disease) kinase and expressed in E. coli.
      FormWhite to off-white solid
      CAS number22189-32-8
      RTECSWG7400000
      Chemical formulaC₁₄H₂₄N₂O₇ · 2HCl · 5H₂O
      Structure formulaStructure formula
      SolubilityH₂O (50 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 8739
      ReferencesThompson, P.R., et al. 1998. J. Biol. Chem. 273, 14788.
      Noah, J., and Wollenzien, P. 1997. Nucleic Acids Symp. Ser. 36, 178.
      Suter, T.M., et al. 1997. Antimicrob. Agents Chemother. 41, 1385.
      Thom, G., and Prescott, C.D. 1997. Bioorg. Med. Chem. 5, 1081.