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Cell Signaling Antibodies & Assays | Life Science Research | Merck
Cell signaling pathways transmit the reactions of cells to various internal and external stimuli. Intracellular signal transduction is often accomplished through a series of reversible protein phosphorylation events. -
Protein Phosphorylation | Life Science Research | Merck
Protein phosphorylation systems are composed of at least three components: (a) phosphoproteins (b) kinases and (c) phosphatases, that dephosphorylate the phosphoproteins, thereby restoring the system to its basal stage. -
Histone Peptide Arrays | Life Science Research | Merck
Histone peptide arrays are essential screening tools to evaluate the specificity and cross-reactivity of antibodies against histones H2A, H2B, H3, H4, and their post-translational modifications.The arrays are designed on PVDF membranes for a simple Western blot-like assay. -
Inflammation & Immunology Antibodies | Life Science Research | Merck
Discover new antibodies and assays for inflammation and immunology and featured products. -
Antibodies for Cytoplasmic Signaling | Life Science Research | Merck
Cytoplasmic signaling proteins play crucial roles in cell cycle, targeted proteolysis, protein trafficking, cytoskeletal organization, and gene expression. -
Antibodies for Extracellular Signaling | Life Science Research | Merck
Extracellular cell signaling is triggered inside the cell trough by binding molecules, such as hormones, pharmacophores, toxins, or neurotransmitters, to the extracellular domains of transmembrane receptors. -
Antibodies for Nuclear Signaling | Life Science Research | Merck
Nuclear signaling regulates gene expression by activating transcriptional activator proteins which can now bind to DNA. -
Post-Translational Modifications | Life Science Research | Merck
Post-translational modifications (PTM) affect signaling proteins which makes the study of cell signaling pathways challenging. Our technologies for signaling research, combined with validated antibodies for proteins and PTMs, enable you to choose the perfect assay. -
Research Areas | Life Science Research | Merck
Antibodies have been a critical tools for most areas of life science research. The basic principle of any immunochemical technique is that a specific antibody will combine with its specific antigen to generate an exclusive antibody-antigen complex. The nature of this bond is a molecular tag for used in every biological research areas. We have a very strong, interactive customer base that continuously requests new or modified antibody targets for research that matters to them. Your research motivates our search for, and development of antibodies that advance science - one target at a time. Our portfolio contains over 10,000 quality antibodies.