11715
Sodium barbiturate
≥97.0% (T)
Synonym(s):
Barbituric acid sodium salt
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About This Item
Empirical Formula (Hill Notation):
C4H3N2NaO3
CAS Number:
Molecular Weight:
150.07
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
224-507-3
Beilstein/REAXYS Number:
3748030
MDL number:
Product Name
Sodium barbiturate, ≥97.0% (T)
InChI key
MHQHHBYRYFICDV-UHFFFAOYSA-M
InChI
1S/C4H4N2O3.Na/c7-2-1-3(8)6-4(9)5-2;/h1H2,(H2,5,6,7,8,9);/q;+1/p-1
SMILES string
[Na+].[O-]C1=NC(=O)NC(=O)C1
assay
≥97.0% (T)
solubility
hot water: soluble 0.2 g/10 mL, clear, colorless
Quality Level
Application
Sodium barbiturate has been used for quantification of thrombin in plasma. It has been used in the estimation of trypsin in duodenal contents. It was also used as a buffer to characterise the functions of two long-chain fatty acid CoA ligase genes (facl) in crude oil-degrading Geobacillus thermodenitrificans NG80-2.
General description
Sodium barbiturate is a white to light beige powder. It accelerates the propagation of metastatic prostate adenocarcinomas in rats and in tissue culture.
Other Notes
Sales restrictions may apply
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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F A Ofosu et al.
Blood, 64(3), 742-747 (1984-09-01)
Heparan with a low affinity for antithrombin III has previously been demonstrated to inhibit thrombin generation in both normal plasma and plasma depleted of antithrombin III. In addition, standard heparin and heparin with a low affinity for antithrombin III have
M Pollard et al.
Oncology, 34(3), 129-132 (1977-01-01)
Metastatic prostate adenocarcinomas, derived from aging germfree Wistar rats, have been propagated in rats and in tissue culture. A protocol has been developed and demonstrated for assay of treatments which retard or which accelerate the rate and extent of tumor
Simple method for estimating trypsin.
H S Wiggins
Gut, 8(4), 415-416 (1967-08-01)
Meike Roth et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 204(1), 50-55 (2010-03-09)
Significant (13)C NMR signal enhancement by a factor of 5000 of a barbituric acid derivative (5-methyl-5-propenyl-barbituric acid) via parahydrogen induced polarization is presented. This hyperpolarization is achieved by hydrogenating 5-methyl-5-propargyl-barbituric acid with 98% enriched para-H(2) under elevated temperature and pressure
Szilvia Hajdok et al.
The Journal of organic chemistry, 74(19), 7230-7237 (2009-09-11)
The laccase-catalyzed reaction between catechols and heterocyclic 1,3-dicarbonyls (pyridinones, quinolinones, thiocoumarins) using aerial oxygen as the oxidant delivers benzofuropyridinones, benzofuroquinolinones, and thiocoumestans in a simple fashion, highly regioselectively with yields ranging from 55 to 98%. With barbituric acid derivatives the
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