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Merck

172472

Isopropyl myristate

98%

Synonym(s):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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About This Item

Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
110-27-0
Molecular Weight:
270.45
NACRES:
NA.22
PubChem Substance ID:
24850403
eCl@ss:
39022421
UNSPSC Code:
12352100
EC Number:
203-751-4
MDL number:
MFCD00008982
Beilstein/REAXYS Number:
1781127

Key Documents

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Product Name

Isopropyl myristate, 98%

Quality Level

100

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

assay

98%

form

liquid

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

functional group

ester

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Application

Isopropyl myristate was used as oil phase in the preparation of formulations. It was also used as oil/water-type tacrolimus (FK506) solvent.

General description

IPM is a fatty acid ester that can be produced by the esterification of isopropyl alcohol and myristic acid.

Storage Class

10 - Combustible liquids

wgk

awg

flash_point_f

>302.0 °F

flash_point_c

> 150 °C

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB6567
SDBB1551
STBL3090
STBL2459
STBL0521

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Neslihan Ustündağ Okur et al.
Chemical & pharmaceutical bulletin, 62(2), 135-143 (2014-02-05)
Naproxen (Np) is an example of a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of pain and inflammation. In order to develop an alternative formulation for the topical administration of Np, microemulsions were evaluated as delivery vehicles. Four
Timothy S McClintock et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(47), 15669-15678 (2014-11-21)
Our understanding of mammalian olfactory coding has been impeded by the paucity of information about the odorant receptors (ORs) that respond to a given odorant ligand in awake, freely behaving animals. Identifying the ORs that respond in vivo to a
Green synthesis of isopropyl myristate in novel single phase medium Part I: Batch optimization studies
Vadgama R, et al.
Biotechnology reports (Amsterdam, Netherlands), 8, 133-137 (2015)
Masayuki Yamanaka et al.
International journal of pharmaceutics, 464(1-2), 19-26 (2014-01-25)
We developed an oil/water-type tacrolimus (FK506) cream formulation as an alternative to Protopic ointment for atopic dermatitis treatment. We determined the effects of solvents used in topical preparations on FK506 solubility and stability, and evaluated FK506 transdermal absorption into rat
Santiago Delgado-Tirado et al.
Scientific reports, 10(1), 20554-20554 (2020-12-02)
Proliferative vitreoretinopathy (PVR) is the leading cause of retinal detachment surgery failure. Despite significant advances in vitreoretinal surgery, it still remains without an effective prophylactic or therapeutic medical treatment. After ocular injury or retinal detachment, misplaced retinal cells undergo epithelial
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