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Merck

207713

1,3-Di-o-tolylguanidine

99%

Synonym(s):

DTG

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About This Item

Linear Formula:
(CH3C6H4NH)2C(=NH)
CAS Number:
97-39-2
Molecular Weight:
239.32
NACRES:
NA.22
PubChem Substance ID:
24852467
UNSPSC Code:
12352100
EC Number:
202-577-6
MDL number:
MFCD00008513

Product Name

1,3-Di-o-tolylguanidine, 99%

InChI key

OPNUROKCUBTKLF-UHFFFAOYSA-N

InChI

1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)

SMILES string

Cc1ccccc1NC(=N)Nc2ccccc2C

assay

99%

form

solid

mp

176-178 °C (lit.)

solubility

water: soluble 70 mg/mL at 20 °C

functional group

amine

Quality Level

100

Gene Information

human ... EBP(10682)

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General description

1,3-Di-o-tolylguanidine is a selective σ-receptor agonist. 1,3-Di-o-tolylguanidine is σ site ligand and its interaction with dopamine drugs were studied in Wistar rats and Albino Swiss mice.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW7506
MKCV7802
MKCW1599
MKCW1600
MKCW8211

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  5. What is the solubility of Product 207713, 1,3-di-o-tolylguanidine?

    1,3-Di-o-tolylguanidine is soluble in water at 70 micrograms per mL at ambient temperature.

  6. What is the nature of the biological activity of Product 207713, 1,3-di-o-tolylguanidine?

    1,3-Di-o-tolylguanidine is known to be a selective ligand for the sigma site in the mammalian central nervous system. Behavioral changes, such as hypothermia, reduced pain behavior, circling behavior, and decreased locomotor activity in mice and/or rats were observed after intraperitoneal, subcutaneous, intravenous and/or intranigral injection.

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