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Merck

423238

(Hydroxypropyl)methyl cellulose

average Mn ~10,000

Synonym(s):

Cellulose hydroxypropyl methyl ether, HPMC, Hypromellose, Methyl hydroxypropyl cellulose

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About This Item

CAS Number:
9004-65-3
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00131360

Key Documents

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Product Name

(Hydroxypropyl)methyl cellulose, average Mn ~10,000

SMILES string

O3[C@H]([C@@H]([C@H]([C@@H]([C@H]3COCC(O)C)OCC(O)C)OCC(O)C)OCC(O)C)O[C@@H]4[C@H](O[C@H]([C@@H]([C@H]4OCC(O)C)OCC(O)C)OCC(O)C)COCC(O)C.O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1COC)OC)OC)OC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OC)OC)OC)COC

InChI key

PUSNGFYSTWMJSK-GSZQVNRLSA-N

form

powder

mol wt

average Mn ~10,000

extent of labeling

1.8-2.0 mol methoxy per mol cellulose (D.S.)
29 wt. % methoxy
0.2-0.3 mol propylene oxide per mol cellulose (M.S.)
7 wt. % propylene oxide

surface tension

43-55 dyn/cm, 25 °C, 0.05 wt. %

viscosity

6 cP(20 °C)(lit.)

transition temp

gel point 58-64 °C

Quality Level

200

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Related Categories

Application

Thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid.

Features and Benefits

  • High-purity grade suitable for demanding industrial and research applications.
  • Offered in powder form easy to handle, measure, and dissolve, ensuring consistent dispersion in aqueous systems.
  • Propylene oxide content: 7 wt.% which improves film-forming and surface activity.
  • Low Molecular weight suitable for low viscosity formulations and improved mixing
Dissolves in water, undergoes reversible gelation upon heating, non-ionic, does not complex with ionic species and is surface active and enzyme resistant. Solutions are pseudoplastic.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ1258
MKCW1186
MKCP6865
MKCM9800
MKCM2740

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Fernando Andrés et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), E2760-E2769 (2014-07-01)
In Arabidopsis thaliana environmental and endogenous cues promote flowering by activating expression of a small number of integrator genes. The MADS box transcription factor SHORT VEGETATIVE PHASE (SVP) is a critical inhibitor of flowering that directly represses transcription of these
Jeonghoon Han et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 308-317 (2014-05-13)
In this study, we investigated the effects of the water-accommodated fraction (WAF) of crude oil on the development and reproduction of the intertidal copepod Tigriopus japonicus through life-cycle experiments. Furthermore, we investigated the mechanisms underlying the toxic effects of WAF
Jane W Agger et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(17), 6287-6292 (2014-04-16)
The recently discovered lytic polysaccharide monooxygenases (LPMOs) are known to carry out oxidative cleavage of glycoside bonds in chitin and cellulose, thus boosting the activity of well-known hydrolytic depolymerizing enzymes. Because biomass-degrading microorganisms tend to produce a plethora of LPMOs
Somayeh Bahrami et al.
Veterinary parasitology, 203(1-2), 43-50 (2014-03-19)
Fasciola gigantica is a parasitic helminth that predominantly infects the liver and bile ducts of cattle and causes great losses of cattle production in the southwestern regions of Iran. The purpose of the present study was to find out the
Youcai Hu et al.
Nature chemical biology, 10(7), 552-554 (2014-05-20)
Despite the remarkable versatility displayed by flavin-dependent monooxygenases (FMOs) in natural product biosynthesis, one notably missing activity is the oxidative generation of carbonate functional groups. We describe a multifunctional Baeyer-Villiger monooxygenase, CcsB, which catalyzes the formation of an in-line carbonate
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