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Merck

674974

6-Mercaptohexanoic acid

90%

Synonym(s):

MHA

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About This Item

Empirical Formula (Hill Notation):
C6H12O2S
CAS Number:
17689-17-7
Molecular Weight:
148.22
NACRES:
NA.23
PubChem Substance ID:
24885247
UNSPSC Code:
12352103
MDL number:
MFCD08705278

Product Name

6-Mercaptohexanoic acid, 90%

InChI

1S/C6H12O2S/c7-6(8)4-2-1-3-5-9/h9H,1-5H2,(H,7,8)

SMILES string

OC(=O)CCCCCS

InChI key

CMNQZZPAVNBESS-UHFFFAOYSA-N

assay

90%

refractive index

n20/D 1.4846

density

1.0715 g/mL at 25 °C

storage temp.

−20°C

Gene Information

rat ... Ace(24310)

Quality Level

100

Related Categories

Application

MHA can be used in the surface modification of InP quantum nanowires for their potential uage in fluorescent chemical sensors that monitor cyanide ions. MHA may also be covalently bonded with liposomes that can form a SAM on the surface of gold for use as an insect odorant receptor in biosensor based applications.
Used to prepare thiol-functionalized 1.5 nm gold nanoparticles via a ligand exchange process with triphenylphosphine-stabilized nanoparticles. This compound is used in self-assembly to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized with various amines and alcohols to introduce more complex end groups. Can also be used to control the rate of aggregation of gold colloidal nanoparticles using pH.

General description

6-Mercaptohexanoic acid (MHA) forms a self-assembled monolayer (SAM) that is used to cap a variety of materials like gold nanoparticles (AuNPs) and indium phosphide quantum dots (InPQDs). It is majorly used in immobilizing the surface molecules, which enhance the physio-chemical and electrical properties.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ1837
MKCX4891
MKCV3351
MKCT2687
MKCR7860

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An Ultrasensitive Electrochemical Impedance-Based Biosensor Using Insect Odorant Receptors to Detect Odorants
Khadka R, et al.
Biosensors And Bioelectronics, 183, 441-445 (2018)
Wenjuan Wei et al.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 50(6), 821-830 (2016-01-05)
Treatment of Acinetobacter baumannii infections is challenging owing to widespread multidrug-resistant A. baumannii (MDR-AB) and the lack of novel agents. Although recent data suggest that levofloxacin (LVX) may have unique activity against MDR-AB in combination with colistin (CST), further preclinical
Panagiotis Papadopoulos et al.
Food microbiology, 84, 103249-103249 (2019-08-20)
Recently, there has been an increased tendency towards raw-milk consumption, which may pose a consumer risk, due to the possible presence of human pathogenic microorganisms, such as Staphylococcus aureus and even methicillin-resistant S. aureus (MRSA). The prevalence of S. aureus
Electrochemical switch on-off response of a self-assembled monolayer (SAM) upon exposure to perfluorooctanoic acid (PFOA)
Fang C, et al.
Journal of Electroanalytical Chemistry, 785, 249-254 (2017)
Electrochemical genoassays on gold-coated magnetic nanoparticles to quantify genetically modified organisms (GMOs) in food and feed as GMO percentage
Placido A, et al.
Biosensors And Bioelectronics, 110, 147-154 (2018)
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