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Merck

81240

Poly(ethylene glycol)

greener alternative

average Mn 4,000, flakes

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
UNSPSC Code:
12352104
PubChem Substance ID:
24887706
NACRES:
NA.23
MDL number:
MFCD00081839

Product Name

Poly(ethylene glycol), average Mn 4,000, flakes

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

form

flakes
powder

mol wt

Mn 3,500-4,500
average Mn 4,000

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

58-61 °C

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

Aligned

Quality Level

200

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Application

Polyethylene glycol (PEG) platelets were used:
  • in PEG-directed gene delivery of protoplast transfection and incubation
  • to prepare extraction for measuring cytosolic phosphoenolpyruvate carboxykinase (PEPCK) from plant tissues
  • as DNA transformation agent in a study of transient gene expression of plant protoplasts, derived from rice leaf sheaths.
  • in preparing isothermal assembly buffer and TSS broth preparation for unique nucleotide sequence (UNS)-guided assembly of repetitive DNA parts
  • in transformation of DNA into log-phase cells of the budding yeast Saccharomyces cerevisiae.
  • as DNA transformation reagent

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels PEG is a suitable material for biological applications because it does not trigger an immune response.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Other Notes

Polymer networks with grafted cell adhesion peptides for highly biospecific cell adhesive substrates

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP0906
BCCN6987
BCCN0140
BCCM2408
BCCK7755

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Oleg Raitskin et al.
PloS one, 14(2), e0211598-e0211598 (2019-02-28)
Molecular tools adapted from bacterial CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats) systems for adaptive immunity have become widely used for plant genome engineering, both to investigate gene functions and to engineer desirable traits. A number of different Cas (CRISPR-associated)
Shen, Jinbo, et al. "Isolation, culture, and transient transformation of plant protoplasts
Shen J, et al.
Current Protocols in Cell Biology, 2014, 2-8 null
A simple and effective method to encapsulate tobacco mesophyll protoplasts to maintain cell viability
Lei R, et al.
Methods, 24-32 (2015)
Jennifer DeMars Tripp et al.
Yeast (Chichester, England), 30(5), 191-200 (2013-03-14)
Chemical-based methods have been developed for transformation of DNA into log-phase cells of the budding yeast Saccharomyces cerevisiae with high efficiency. Transformation of early stationary-phase cells, e.g. cells grown in overnight liquid cultures or as colonies on plates, is less
P D Drumheller et al.
Analytical biochemistry, 222(2), 380-388 (1994-11-01)
Polymer networks of poly(ethylene glycol) (PEG) in densely cross-linked matrices of acrylic acid (AA) and trimethylolpropane triacrylate were synthesized as biospecific cell adhesive substrates. Networks grafted with synthetic adhesion peptides produced substrates to investigate long-term, receptor-mediated cell/surface interactions, without nonspecific
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