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Merck

857653

trans-4-(Aminomethyl)cyclohexanecarboxylic acid

97%

Synonym(s):

AMCA, AMCHA, HAKU, TAMCHA, Tranexamic acid

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About This Item

Linear Formula:
H2NCH2C6H10CO2H
CAS Number:
1197-18-8
Molecular Weight:
157.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24888448
EC Number:
214-818-2
Beilstein/REAXYS Number:
2207452
MDL number:
MFCD00001466

Product Name

trans-4-(Aminomethyl)cyclohexanecarboxylic acid, 97%

InChI key

GYDJEQRTZSCIOI-LJGSYFOKSA-N

InChI

1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-

SMILES string

NC[C@H]1CC[C@@H](CC1)C(O)=O

assay

97%

form

powder

mp

>300 °C (lit.)

functional group

amine
carboxylic acid

Quality Level

200

Gene Information

human ... PLG(5340)

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Application

Used as a lysine analogue to characterize binding sites in plasminogen.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB4516
SDBB2341
STBL3493
STBJ7761
STBK9826

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Thomas Forro et al.
Cerebral cortex (New York, N.Y. : 1991), 25(5), 1228-1240 (2013-11-28)
Travelling theta oscillations and sharp wave-associated ripples (SWRs) provide temporal structures to neural activity in the CA1 hippocampus. The contribution of rhythm-generating GABAergic interneurons to network timing across the septotemporal CA1 axis remains unknown. We recorded the spike-timing of identified
Kristen A Matteson et al.
Obstetrics and gynecology, 121(3), 632-643 (2013-05-03)
To compare the effectiveness of nonsurgical abnormal uterine bleeding treatments for bleeding control, quality of life (QOL), pain, sexual health, patient satisfaction, additional treatments needed, and adverse events. MEDLINE, Cochrane databases, and Clinicaltrials.gov were searched from inception to May 2012.
J M Marshall et al.
Biochemistry, 33(12), 3599-3606 (1994-03-29)
The conformations of Glu-plasminogen and defined proteolytic fragments, in the presence and absence of 6-aminohexanoic acid (6-AHA), trans-4-(aminomethyl)cyclohexanecarboxylic acid (t-AMCHA), and benzamidine, were studied using three methods: size-exclusion high-performance liquid chromatography (SE-HPLC), small-angle X-ray scattering (SAXS), and dynamic laser light
Case scenario: management of trauma-induced coagulopathy in a severe blunt trauma patient.
Jean-Stephane David et al.
Anesthesiology, 119(1), 191-200 (2013-03-22)
G J Hoover et al.
Biochemistry, 32(41), 10936-10943 (1993-10-19)
A series of strategically designed recombinant (r) mutants of the kringle 1 region of human plasminogen ([K1HPg]) have been constructed and the resulting gene products employed to reveal the identities of the residues that contribute to stabilization of the binding
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