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Merck

H50004

4-Hydroxyphenylacetic acid

98%

Synonym(s):

(4-Hydroxyphenyl)acetic acid, (p-Hydroxyphenyl)acetic acid, 2-(4′-Hydroxyphenyl)acetic acid, 2-[4-(Hydroxy)phenyl]acetic acid, 4-(Carboxymethyl)phenol, 4-Hydroxybenzeneacetic acid, 4′-Hydroxyphenylacetic acid, p-Hydroxybenzeneacetic acid

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About This Item

Linear Formula:
HOC6H4CH2CO2H
CAS Number:
Molecular Weight:
152.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-851-3
Beilstein/REAXYS Number:
1448766
MDL number:

Product Name

4-Hydroxyphenylacetic acid, 98%

SMILES string

OC(=O)Cc1ccc(O)cc1

InChI

1S/C8H8O3/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11)

InChI key

XQXPVVBIMDBYFF-UHFFFAOYSA-N

assay

98%

mp

148-151 °C (lit.)

Quality Level

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Application

Reagent used in the acylation of phenols and amines.

General description

4-Hydroxyphenylacetic acid is a phenolic acid that is esterified with various alcohols to synthesize esters.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Journal of the Chemical Society. Perkin Transactions 1, 3005-3005 (1991)
Characterization of negative tone photoresist based on acid catalyzed dehydration crosslinking of novolac resins having pendant carboxyl groups
Liu HH, et al.
Journal of Polymer Research, 9, 251-256 (2002)
Korean J. Med. Chem., 1, 2-2 (1991)
Matthew Snelson et al.
Science advances, 7(14) (2021-04-02)
Intake of processed foods has increased markedly over the past decades, coinciding with increased microvascular diseases such as chronic kidney disease (CKD) and diabetes. Here, we show in rodent models that long-term consumption of a processed diet drives intestinal barrier
Kenneth Stensrud et al.
The Journal of organic chemistry, 74(15), 5219-5227 (2009-07-04)
Three new trifluoromethylated p-hydroxyphenacyl (pHP)-caged gamma-aminobutyric acid (GABA) and glutamate (Glu) derivatives have been examined for their efficacy as photoremovable protecting groups in aqueous solution. Through the replacement of hydrogen with fluorine, e.g., a m-trifluoromethyl or a m-trifluoromethoxy versus m-methoxy

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