W527602

L-Isoleucine

Name: <SC>L</SC>-Isoleucine
Brand: ALDRICH

99%, FCC, FG

Synonym(s):

(2S,3S)-2-Amino-3-methylpentanoic acid

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About This Item

Linear Formula:

C₂H₅CH(CH₃)CH(NH₂)CO₂H

CAS Number:

73-32-5

Molecular Weight:

131.17

NACRES:

NA.21

PubChem Substance ID:

24902116

eCl@ss:

32160406

UNSPSC Code:

12164502

EC Number:

200-798-2

MDL number:

MFCD00064222

Beilstein/REAXYS Number:

1721792

organoleptic:

odorless

grade:

biological source:

synthetic

food allergen:

no known allergens

Product Name

L-Isoleucine, 99%, FCC, FG

InChI key

AGPKZVBTJJNPAG-WHFBIAKZSA-N

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1

SMILES string

CC[C@H](C)[C@H](N)C(O)=O

biological source

synthetic

grade

reg. compliance

EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 172.320

assay

99%

form

crystalline powder

optical activity

[α]20/D +38.6 to +42.5°, c = 4 in 6 M HCl

mp

288 °C (dec.) (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

Quality Level

300

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Related Categories

Flavors & Fragrances

Application

Enhanced protein-metabolite correlation analysis: To investigate the association between Staphylococcus aureus mastitis and metabolic immune pathways.: This article discusses the metabolic pathways associated with bacterial infections in livestock, potentially useful for chemists studying metabolic pathways and their linkage to immune responses (Chen et al., 2024).

Probing pharmaceutically important amino acids L-isoleucine and L-tyrosine Solubilities: Unraveling the solvation thermodynamics in diverse mixed solvent systems.: This study explores the solubility and solvation thermodynamics of l-isoleucine, providing critical data for chemists working with pharmaceutical formulations and solubility studies (Chakraborty et al., 2024).

General description

L-Isoleucine is an essential amino acid used as a supplement in sports nutrition. It is one of the free-amino acids found in common buckwheat.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Zorn H and Czermak P

Biotechnology of Food and Feed Additives., 219-220 null

Flavor components in buckwheat bread

Lin LY, et al

Journal of Food Processing and Preservation, 33(6), 814-826 (2009)

Long-term leisure-time physical activity and serum metabolome.

Urho M Kujala et al.

Circulation, 127(3), 340-348 (2012-12-22)

Long-term physical inactivity seems to cause many health problems. We studied whether persistent physical activity compared with inactivity has a global effect on serum metabolome toward reduced cardiometabolic disease risk. Sixteen same-sex twin pairs (mean age, 60 years) were selected

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2.

Anna L Vestergaard et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(14), E1334-E1343 (2014-04-08)

P4-ATPases (flippases) translocate specific phospholipids such as phosphatidylserine from the exoplasmic leaflet of the cell membrane to the cytosolic leaflet, upholding an essential membrane asymmetry. The mechanism of flipping this giant substrate has remained an enigma. We have investigated the

Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise.

Eva Blomstrand et al.

The Journal of nutrition, 136(1 Suppl), 269S-273S (2005-12-21)

BCAAs (leucine, isoleucine, and valine), particularly leucine, have anabolic effects on protein metabolism by increasing the rate of protein synthesis and decreasing the rate of protein degradation in resting human muscle. Also, during recovery from endurance exercise, BCAAs were found

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