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Key Documents

06-227

Sigma-Aldrich

Anti-TGFβR Type II Antibody, NT

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

Gene Information

human ... TGFBR2(7048)

General description

75kDa

Immunogen

peptide corresponds to the first 28 N-Terminal residues of the mature human TGFb receptor

Application

Detect TGFβR Type II using this Anti-TGFβR Type II Antibody, NT validated for use in IH, IP & WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Biochem/physiol Actions

p75 TGFb Type II receptors

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Chromatography

Preparation Note

2 years at 2-8°C

Analysis Note

routinely evaluated by immunoblot on TF-1 cell lysate, WI-38 human diploid fibroblasts or on rat L6 cell lysate

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10-13 - German Storage Class 10 to 13


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Roles of the transforming growth factor beta 1 and its type I and II receptors in the development of a pulmonary adenocarcinoma: results of an immunohistochemical study.
I Takanami, F Tanaka, T Hashizume, S Kodaira
Journal of Surgical Oncology null
Dysfunctional transforming growth factor-beta receptor II accelerates prostate tumorigenesis in the TRAMP mouse model.
Pu, H; Collazo, J; Jones, E; Gayheart, D; Sakamoto, S; Vogt, A; Mitchell, B; Kyprianou, N
Cancer Research null
H Y Lin et al.
Cell, 68(4), 775-785 (1992-02-21)
A cDNA encoding the TGF-beta type II receptor protein has been isolated by an expression cloning strategy. The cloned cDNA, when transfected into COS cells, leads to overexpression of an approximately 80 kd protein that specifically binds radioiodinated TGF-beta 1.
Expression of cytokine receptors on follicular dendritic cells
Yamada, K., et al
Blood, 90, 4832-4841 (1997)
Osmotic shock stimulates GLUT4 translocation in 3T3L1 adipocytes by a novel tyrosine kinase pathway
Chen, D., et al
The Journal of Biological Chemistry, 272, 27401-27410 (1997)

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