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Key Documents

07-723

Sigma-Aldrich

Anti-Apobec3 Antibody, NT

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

Gene Information

human ... APOBEC3F(200316)

General description

51kDa An additional protein was also detected, Mr 31kDa

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 82-95 (C-DKVLKVLSPREEFK) of mouse apolipoprotein B editing complex 3 (Apobec3), with an N-terminal cysteine added for conjugation purposes.

Application

Anti-Apobec3 Antibody, NT is a high quality Rabbit Polyclonal Antibody for the detection of Apobec3 & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Biochem/physiol Actions

Apobec3

Physical form

Affinity purified antibody in 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.
ImmunoAffinity Purified

Preparation Note

Maintain for 1 year at 2 to 8°C from date of shipment.

Analysis Note

Routinely evaluated by immunoblot.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10-13 - German Storage Class 10 to 13


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Adam Jarmuz et al.
Genomics, 79(3), 285-296 (2002-02-28)
The cytidine (C) to uridine (U) editing of apolipoprotein (apo) B mRNA is mediated by tissue-specific, RNA-binding cytidine deaminase APOBEC1. APOBEC1 is structurally homologous to Escherichia coli cytidine deaminase (ECCDA), but has evolved specific features required for RNA substrate binding
Ann M Sheehy et al.
Nature, 418(6898), 646-650 (2002-08-09)
Viruses have developed diverse non-immune strategies to counteract host-mediated mechanisms that confer resistance to infection. The Vif (virion infectivity factor) proteins are encoded by primate immunodeficiency viruses, most notably human immunodeficiency virus-1 (HIV-1). These proteins are potent regulators of virus
Yong-Hui Zheng et al.
Journal of virology, 78(11), 6073-6076 (2004-05-14)
Recently, APOBEC3G has been identified as a host factor that blocks retroviral replication. It introduces G to A hypermutations in newly synthesized minus strand viral cDNA at the step of reverse transcription in target cells. Here, we identified the human

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