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Cellvento® ModiFeed Gal+ COMP

Chemically defined cell culture feed - EMPROVE® CCM

greener alternative

Greener Alternative

Synonym(s):

CHO Galactosylation Feed, Cellvento® Gal+ feed, Cellvento® ModiFeed Gal+, Galactosylation Modulating Feed

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About This Item

UNSPSC Code:
41106213
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Product Name

Cellvento® ModiFeed Gal+ COMP, Chemically defined, CHO fed-batch feed to increase galactosylation, EMPROVE® CCM

Quality Segment

500

biological source

non-animal source

description

shipped with cooling packs

product line

Cellvento®

form

compacted dry powder

greener alternative product characteristics

Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

cell culture | mammalian: suitable

application(s)

pharma/biopharma processes

components

glucose: no

greener alternative category

DfS-Developed

storage temp.

2-8°C

General description

Cellvento® ModiFeed Gal+ COMP is a chemically defined, animal-origin-free, highly concentrated fed-batch feed designed to maximize galactosylation of monoclonal antibodies (mAbs) and recombinant proteins in CHO cell-based expression systems. Part of the Cellvento® ModiFeed platform, this one-part, pH-neutral feed is supplied as a compacted dry powder. The formulation contains no glucose, no hydrolysates, no phenol red, and no 2-mercaptoethanol, ensuring high batch-to-batch consistency and process control. On combination with Cellvento® ModiFeed Prime it allows tunable galactosylation.

Cellvento® ModiFeed Gal+ COMP supported by the Emprove® Program and designated DfS, making it suitable for scalable, quality-focused biologics manufacturing workflows.

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.

Application

Cellvento® ModiFeed Gal+ COMP is used for:
  • Maximizing galactosylation of mAbs and recombinant proteins in CHO fed-batch processes, while maintaining or improving product titer
  • Controlling protein glycosylation, a critical quality attribute affecting biological activity, solubility, serum half-life, and safety of therapeutic proteins
  • Targeting specific galactosylation profiles when mixed with Cellvento® ModiFeed Prime, ideal for biosimilar development

Features and Benefits

  • Complete feed maximizing galactosylation
  • One-part, pH-neutral complete feed for simplified fed-batch process
  • Maximizes terminal galactosylation without compromising titer
  • Highly concentrated to reduce feed volume added to bioreactor
  • Compacted powder for convenient handling and easy hydration
  • Ambient-stable hydrated solution up to 30 days
  • Chemically defined, no animal-origin components
  • No glucose enabling precise glucose control
  • Supported by EMPROVE® CCM Program

Preparation Note

Formulated to contain 159.9 grams of powder per liter of feed.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

wgk

WGK 3

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