124019
Akt Inhibitor IX, API-59CJ-OMe - CAS 98510-80-6 - Calbiochem
Synonym(s):
MMEA, 9-Methoxy-2-methylellipticinium acetate, NSC 627505
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About This Item
UNSPSC Code:
12352200
General description
A cell-permeable ellipticine compound that potently and selectively induces apoptosis in human endometrial cancer cells (RL95-2 and Ishikawa) that exhibit elevated Akt activity (effective concentration = 12-24 μM), but not on cells with low Akt activity. Directly affects the activity by Akt, but not the level of cellular phosphorylation of Akt, ERK1/2, JNK1/2, PDK1, PKC isoforms, or serum and glucocorticoid-inducible kinase (SGK).
The Akt Inhibitor IX, API-59CJ-OMe controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Biochem/physiol Actions
Target IC50:12-24 μM against Akt
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Storage Class Code
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
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