Assay
≥90% (by absorbance)
form
lyophilized solid
color
white
solubility
H2O: 10 mg/mL
methanol: soluble
General description
α-Amanitin, Amanita sp. is a toxic bicyclic octapeptide isolated from mushrooms. A potent & specific inhibitor of RNA polymerase II and messenger RNA synthesis in higher eukaryotes.
Toxic bicyclic octapeptide isolated from mushrooms. Acts as a potent and specific inhibitor of RNA polymerase II and messenger RNA synthesis in higher eukaryotes, including animals and plants.
Biochem/physiol Actions
RNA polymerase 2
Preparation Note
Reconstitute to a concentration ≥1 mM
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 1 Oral - STOT RE 2
Target Organs
Kidney,Blood,Liver,Gastrointestinal tract,Respiratory Tract,Central nervous system
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Certificates of Analysis (COA)
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