176900
Anthrax Lethal Factor, Recombinant, Bacillus anthracis, B. anthracis - Calbiochem
About This Item
form
lyophilized
Quality Level
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
ambient
storage temp.
2-8°C
General description
This product has been discontinued.
Recombinant, Bacillus anthracis anthrax lethal factor expressed in a specialized strain of B. anthracis. One of the three protein components of Anthrax toxin, lethal factor (LF) is a highly specific protease that cleaves members of the mitogen-activated protein kinase kinase (MAPKK) family. LF is comprised of four domains. Domain I binds the protective antigen to enter the target cell; domains II, III, and IV create a long groove to hold and cleave the MAPKK proteins.
Biochem/physiol Actions
MAPKK
Packaging
Physical form
Preparation Note
Analysis Note
Other Notes
Friedlander, A.M. 2001. Nature414, 160.
Gupta, P., et al. 2001. Biochem. Biophys. Res. Commun.284, 568.
Pannifer, A.D., et al. 2001. Nature414, 160.
Pugsley, A.P. 1996. Proc. Natl. Acad. Sci. USA93, 8155.
Leppla, S.H. 1991. Methods Enzymol.195, 153.
Legal Information
Disclaimer
Storage Class Code
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
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