218742
Caspase Inhibitor I, Biotin Conjugate
The Caspase Inhibitor I, Biotin Conjugate controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
Synonym(s):
Caspase Inhibitor I, Biotin Conjugate, Biotin-X-VAD-FMK
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About This Item
Empirical Formula (Hill Notation):
C30H49FN6O8S
Molecular Weight:
672.81
NACRES:
NA.54
UNSPSC Code:
12352200
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
brown
solubility
DMSO: 20 mM
shipped in
ambient
storage temp.
−20°C
General description
Biotinylated derivative of Caspase Inhibitor I (Cat. No. 627610 ) that may be used to identify active caspases in cell lysates.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Caspase
Caspase
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Analysis Note
single spot by TLC
Other Notes
Biotin-X-Val-Ala-Asp(OMe)-CH₂F* (X = linker)
Li, S. et al. 1999. J. Biol. Chem.274, 17325.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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