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235421

Sigma-Aldrich

Caspase-3 Inhibitor IV - CAS 259199-63-8 - Calbiochem

Synonym(s):

Caspase-3 Inhibitor IV - CAS 259199-63-8 - Calbiochem, Ac-DMQD-CHO

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About This Item

Empirical Formula (Hill Notation):
C20H31N5O10S
CAS Number:
259199-63-8
Molecular Weight:
533.55
UNSPSC Code:
12352200

Assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

DMSO: 5 mg/mL
water: soluble

shipped in

ambient

storage temp.

−20°C

General description

This product has been discontinued.



A specific inhibitor of caspase-3. This tetrapeptide inhibitor has been used with the caspase-6 inhibitor Ac-VEID-CHO to dissect the pathway of caspase activation in Fas-stimulated Jurkat cells.

A specific caspase-3 inhibitor. This tetrapeptide inhibitor has been used with the caspase-6 inhibitor Ac-VEID-CHO (Cat. No. 218758) to dissect the pathway of caspase activation in Fas-stimulated Jurkat cells.

Biochem/physiol Actions

Cell permeable: no
Primary Target
caspase-3
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Ac-Asp-Met-Gln-Asp-CHO
Hirata, H., et al. 1998. J. Exp. Med. 187, 587.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

10-13 - German Storage Class 10 to 13

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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