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Key Documents

324856

Sigma-Aldrich

EGF, Murine Submaxillary Glands, Receptor Grade

Synonym(s):

EGF, Murine Submaxillary Glands, Receptor Grade, Epidermal Growth Factor

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About This Item

CAS Number:
UNSPSC Code:
12352202

Assay

≥98% (SDS-PAGE)

Quality Level

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

shipped in

ambient

storage temp.

2-8°C

General description

Effective biological range: 5-50 ng/ml.
Native epidermal growth factor from mouse submaxillary glands. Mitogenic for a wide range of ectoderm- and endoderm-derived cells from tissue such as breast, cornea, epidermis, dermis, liver, pancreas, nerve, amnion, and adrenal medulla. Purified by size-exclusion chromatography followed by DEAE ion-exchange chromatography.
Native epidermal growth factor from mouse submaxillary glands. Purified by size-exclusion chromatography. Exhibits mitogenic activity in a wide range of tissues of ectodermal and endodermal origin. Effective at concentrations ranging from 5-50 ng/ml.

Biochem/physiol Actions

determined by mitogenic assay with human foreskin fibroblasts

Preparation Note

Reconstitute in culture medium, buffer, H₂O, or 100 mM acetic acid. Wipe the vial with 70% ethanol, add solvent, and swirl gently to dissolve.

Other Notes

Canals, F., et al. 1992. Biochemistry31, 4493.
Cohen, S. 1987. In Vitro Cell. Dev. Biol.23, 239.
Sato, J., et al. 1987. Methods Enzymol.146, 63.
Savage, C.R., and Cohen, S. 1972. J. Biol. Chem.247, 7609.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

10-13 - German Storage Class 10 to 13


Certificates of Analysis (COA)

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