343023
Flt3 Inhibitor IV - CAS 819058-89-4 - Calbiochem
The Flt3 Inhibitor IV, also referenced under CAS 819058-89-4, controls the biological activity of Flt3.
Synonym(s):
Flt3 Inhibitor IV - CAS 819058-89-4 - Calbiochem, 4-(4-Aminophenyl)-1H-indazol-3-ylamine
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About This Item
Empirical Formula (Hill Notation):
C13H12N4
CAS Number:
Molecular Weight:
224.26
UNSPSC Code:
12352200
Quality Level
Assay
≥97% (HPLC)
form
solid (Glassy)
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
brown
solubility
DMSO: 100 mg/mL
ethanol: 30 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
A 3-aminoindazole compound that acts as a potent and ATP-competitive inhibitor of Flt3 (IC50 = 43 nM) with excellent selectivity over KDR/VEGFR-2 and c-Kit (IC50 = 4.79 µM and 7.36 µM, respectively).
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Dai, Y., et al. 2007. J. Med. Chem.50, 1584.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Regulatory Review (Z)
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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