36-003
Anti-phospho-MYPT1 (Thr850) Antibody
Upstate®, from rabbit
Synonym(s):
Anti-GUBS, Anti-M130, Anti-MBS, Anti-MYPT1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Product Name
Anti-phospho-MYPT1 (Thr850) Antibody, Upstate®, from rabbit
biological source
rabbit
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
chicken, rat, human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pThr850)
Quality Level
Gene Information
human ... PPP1R12A(4659)
General description
80 kDa
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Protein A Purified rabbit IgG in a solution of 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.135M NaCl, and 0.035% sodium azide as a preservative.
Protein A purified
Analysis Note
Control
MYPT1 substrate phosphorylated by ROKa/ROCK-II
MYPT1 substrate phosphorylated by ROKa/ROCK-II
Routinely evaluated by immunoblot on phophorylated MYPT1 substrate
Application
Detect phospho-MYPT1 (Thr850) using this Anti-phospho-MYPT1 (Thr850) Antibody validated for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
Kinases & Phosphatases
Kinases & Phosphatases
Biochem/physiol Actions
Recombinant truncated chicken MYPT1 phosphorylated on Thr850.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Peptide corresponding to amino acid residues 845-855 of chicken MYPT1; this sequence is identical to amino acids 848-858 of human MYPT1, with the phosphorylated Thr at position 853.
Preparation Note
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Nandy C Lopez et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 310(11), R1053-R1063 (2016-02-26)
Exposure to high-altitude chronic hypoxia during pregnancy may cause pulmonary hypertension in neonates, as a result of vasoconstriction and vascular remodeling. We hypothesized that susceptibility to pulmonary hypertension, due to an augmented expression and activity of the RhoA/Rho-kinase (ROCK) pathway
An extract from brown rice inhibits signal transduction of angiotensin iI in vascular smooth Muscle cells.
Utsunomiya H, Takaguri A, Bourne AM, Elliott KJ, Akazawa S, Okuno Y, Kono R, Eguchi S
American Journal of Hypertension null
Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease.
Nichols, RJ; Dzamko, N; Hutti, JE; Cantley, LC; Deak, M; Moran, J; Bamborough, P; Reith et al.
The Biochemical Journal null
Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery.
Soo-Kyoung Choi,Duck-Sun Ahn,Young-Ho Lee
Cardiovascular Research null
Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.
Xu, EZ; Kantores, C; Ivanovska, J; Engelberts, D; Kavanagh, BP; McNamara, PJ; Jankov, RP
American Journal of Physiology. Heart and Circulatory Physiology null
Related Content
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 36-003 | 04053252331756 |
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