Key Documents
371727
Anti-Giα-2-Subunit, Internal (85-100) Rabbit pAb
liquid, Calbiochem®
Sign Into View Organizational & Contract Pricing
Select a Size
All Photos(1)
About This Item
UNSPSC Code:
12352203
biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human, rat, mouse
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
wet ice
storage temp.
−70°C
General description
Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the Giα-2-subunit protein.
Recognizes the Giα-2-subunit. Does not cross-react with recombinant Giα-1-, Giα-3-, Goα-, Gqα-, Gsα-, Gtα-1-, or G11α-subunits.
This Anti-Giα-2-Subunit, Internal (85-100) Rabbit pAb is validated for use in ELISA, Immunoblotting for the detection of Giα-2-Subunit, Internal (85-100).
Immunogen
Human, Mouse, Rat
a synthetic peptide (CVKAMGNLQIDFADPQR) corresponding to amino acids 85-100 of human, mouse, and rat Giα-2, conjugated to KLH
Application
ELISA (1:4000)
Immunoblotting (1:2000)
Immunoblotting (1:2000)
Other Notes
Does not cross-react with recombinant Giα-1-, Giα-3-, Goα-, Gqα-, Gsα-, Gtα-1-, or G11α- subunits. Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Andrejs M Krumins et al.
The Journal of biological chemistry, 281(15), 10250-10262 (2006-02-01)
Heterotrimeric G protein signaling specificity has been attributed to select combinations of Galpha, beta, and gamma subunits, their interactions with other signaling proteins, and their localization in the cell. With few exceptions, the G protein subunit combinations that exist in
Nolwenn Merlet et al.
PloS one, 8(5), e64711-e64711 (2013-06-07)
The toxicity of doxorubicin, leading to an irreversible heart failure, limits its use as chemotherapeutic agent. The beneficial effects of early administration of β-blocker were reported in patients with heart failure due to doxorubicin, suggesting an important role of β-adrenoceptors
Jacob Ngai et al.
BMC immunology, 10, 27-27 (2009-05-12)
TCR and CXCR4-mediated signaling appears to be reciprocally regulated pathways. TCR activation dampens the chemotactic response towards the CXCR4 ligand CXCL12, while T cells exposed to CXCL12 are less prone to subsequent TCR-activation. The heterotrimeric G proteins Galphaq and Galphai2
Jacob Ngai et al.
European journal of immunology, 38(11), 3208-3218 (2008-11-11)
Here, we examined the functional involvement of heterotrimeric G-proteins in TCR-induced immune responses. TCR/CD3 crosslinking resulted in activation of both Galphaq and Galphas, but not Galphai-2. Targeting of Galphas, Galphai-2 and Galphaq using siRNA demonstrated a specific role of Galphaq
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service