480354
7S NGF, Mouse Submaxillary Glands
Synonym(s):
7S Nerve Growth Factor
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352202
form
lyophilized
Quality Level
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
EGF, none detected
solubility
neutral buffer: 1 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
Native 7S nerve growth factor from mouse submaxillary glands. Promotes neuron survival and neurite outgrowth in newborn rat brain. Composed of three subunits (α:β:γ) 2:1:2. The α-subunit is an inactive serine proteinase and the γ-subunit is an active serine proteinase capable of processing the precursor form of β-NGF.
Native 7S nerve growth factor from mouse submaxillary glands. Promotes neuron survival and neurite outgrowth in newborn rat brain. Composed of three subunits: (α: β: γ): 2:1:2. The α-subunit is an inactive serine proteinase and the γ-subunit is an active serine proteinase capable of processing the precursor form of β-NGF.
Biochem/physiol Actions
ED₅₀: Determined by half maximal growth of PC12 cells. Please see vial label for lot-specific ED₅₀.
Physical form
Lyophilized from sterile H₂O.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 2 weeks at -20°C.
The 7S NGF complex will dissociate in acidic or basic buffers, so it is critical that the pH of the reconstitution buffer be neutral.
Other Notes
Bax, B., et al. 1997. Structure 5, 1275.
Shao, N., et al. 1993. Brain Res. 609, 338.
Varon, S., et al. 1972. Methods Neurochem.3, 203.
Shao, N., et al. 1993. Brain Res. 609, 338.
Varon, S., et al. 1972. Methods Neurochem.3, 203.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class Code
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service