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About This Item
Empirical Formula (Hill Notation):
C24H40O3
CAS Number:
Molecular Weight:
376.57
UNSPSC Code:
12352200
MDL number:
assay
≥98% (HPLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
clear colorless
solubility
DMSO: 30 mg/mL
storage temp.
−20°C
InChI
1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20+,22+/m1/s1
InChI key
YNZFFALZMRAPHQ-CBQOVEMMSA-N
General description
A potent, non-selective agonist for cannabinoid (CB) receptors (Ki = 0.6 - 5.0 and 0.7 - 2.6 nM for CB1 and CB2 respectively; EC50 = 0.2, 0.3 and 5 nM for CB1, CB2 and GRP55 respectively). Often used in reference or control trials in CB research and the effects are robust in both behavioral tests and receptor binding assays.
A potent, non-selective agonist for cannabinoid (CB) receptors (Ki = 0.6 - 5.0 and 0.7 - 2.6 nM for CB1 and CB2 respectively; EC50 = 0.2, 0.3 and 5 nM for CB1, CB2 and GRP55 respectively). Often used in reference or control trials in CB research and the effects are robust in both behavioral tests and receptor binding assays.
Biochem/physiol Actions
Primary Target
CB receptors
CB receptors
Target Ki: 0.6 - 5.0 and 0.7 - 2.6 nM for CB₁ and CB₂ respectively.
Physical form
Supplied in methanol.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Wiley, J., et al. 1995. Neuropharmacology.34, 669.
Griffin, G., et al. 1998. J. Pharmacol. Exp. Ther.285, 553.
Thomas, B., et al. 1998. J. Pharmacol. Exp. Ther.285, 285.
Avdesh, A., et al. 2012. Psychopharmacology (Berl).220, 405.
Griffin, G., et al. 1998. J. Pharmacol. Exp. Ther.285, 553.
Thomas, B., et al. 1998. J. Pharmacol. Exp. Ther.285, 285.
Avdesh, A., et al. 2012. Psychopharmacology (Berl).220, 405.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Storage Class
3 - Flammable liquids
wgk
WGK 2
Certificates of Analysis (COA)
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