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Key Documents

COA/COQ

539808

PRL-3 Inhibitor - CAS 893449-38-2 - Calbiochem

Name: PRL-3 Inhibitor - CAS 893449-38-2 - Calbiochem
Brand: MM

Synonym(s):

PRL-3 Inhibitor - CAS 893449-38-2 - Calbiochem, 1-(2-Bromobenzyloxy)-4-bromo-2-benzylidene rhodanine

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₁₁Br₂NO₂S₂

CAS Number:

893449-38-2

Molecular Weight:

485.21

MDL number:

MFCD11045303

UNSPSC Code:

12352200

Assay

≥98% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze
protect from light

color

yellow

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

This product has been discontinued.

A cell-permeable benzylidene rhodanine compound that potently inhibits hPRL-3 (IC₅₀ = 900 nM), a member of the regenerating liver family tyrosine phosphatases. Shown to reduce the invasiveness of murine melanoma B16F10 cells.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
hPRL-3

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 900 nM against hPRL-3

Packaging

Packaged under inert gas

Preparation Note

Slight warming may be necessary for complete solubilization.

Other Notes

Ahn, J.H., et al. 2006. Bioorg. Med. Chem. Lett.16, 2996.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

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