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Key Documents

672081

Sigma-Aldrich

Urokinase, High Molecular Weight, Human Urine

Synonym(s):

uPA

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About This Item

EC Number:
UNSPSC Code:
12352202

Assay

≥95% (SDS-PAGE)

Quality Level

form

lyophilized

specific activity

≥60,000 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

pI 

8.4 - 8.9

shipped in

ambient

storage temp.

−20°C

General description

Native, high molecular weight urokinase from human urine. A serine protease that acts as a thrombolytic agent.

Physical form

Lyophilized from 200 mM mannitol, 100 mM NaCl, 50 mM Tris-HCl, 0.1% PEG, pH 7.4.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Prepared from urine that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitute in 1.0 ml of distilled H₂O

Other Notes

Cheung, T., et al. 1993. J. Lab. Clin. Med. 121, 461.
Bacharach, E., et al. 1992. Proc. Natl. Acad. Sci. USA89, 10686.
Franco, P., et al. 1992. J. Biol. Chem.267, 19369.
Granger, C.B., et al. 1992. Drugs44, 293.
Keski-Oja, J., et al. 1992. Exp. Cell Res.202, 471.
Seiffert, D., et al. 1992. Thromb. Haemost.68, 657.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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