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Merck

ECM551

QCM Collagen Cell Invasion Assay, 24-well (8 µm), Colorimetric

The Cell Invasion Assay Kit kuses a 24 well plate with 8 um pores, which is ideal for evaluation of invasive tumor cells.

Synonym(s):

Cell invasion kit

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About This Item

UNSPSC Code:
12352207
eCl@ss:
32161000
NACRES:
NA.32

Quality Level

100

species reactivity

vertebrates

manufacturer/tradename

Chemicon®
QCM

technique(s)

cell based assay: suitable

detection method

colorimetric

shipped in

wet ice

Related Categories

Application

Research Category
Cell Structure
The CHEMICON Cell Invasion Assay Kit is ideal for evaluation of invasive tumor cells. Each CHEMICON Cell Invasion Assay Kit contains sufficient reagents for the evaluation of 24 samples. The quantitative nature of this assay is especially useful for screening of pharmacological agents.

The CHEMICON Cell Invasion Assay Kit is intended for research use only; not for diagnostic or therapeutic applications.

Packaging

24 wells

Preparation Note

Store kit materials at 2-8°C for up to their expiration date. Do not freeze.

Other Notes

Sterile 24-well Cell Invasion Plate Assembly: (Part No. 90248) Two 24-well plates with 12 collagen-coated inserts per plate (24 inserts total/kit).

Cell Stain: (Part No. 90144) One 20 mL bottle.

Extraction Buffer: (Part No. 90145) One 20 mL bottle.

Cotton Swabs: (Part No. 10202) 50 each.

Forceps: (Part No. 10203) One each.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

Flash Point(F)

53.6 °F

Flash Point(C)

12 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Use of a reconstituted basement membrane to measure cell invasiveness and select for highly invasive tumor cells.
Terranova, V P, et al.
Proceedings of the National Academy of Sciences of the USA, 83, 465-469 (1986)
A new in vitro assay for quantitating tumor cell invasion.
Repesh, L A
Invasion & Metastasis, 9, 192-208 (1989)
Dana El-Chami et al.
Oncology letters, 21(2), 163-163 (2021-02-09)
Breast cancer is the leading cause of cancer-associated death among women worldwide. Targeting breast cancer cell metastasis is an important therapeutic approach. The MAPK pathway is a key cell signaling pathway that plays a pivotal role in cellular invasion and
MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF.
Chao Zou,Qing Xu,Feng Mao,Dan Li,Chuanxiu Bian,Ling-Zhi Liu,Yue Jiang,Xiaona Chen et al.
Cell Cycle null
A rapid in vitro assay for quantitating the invasive potential of tumor cells.
Albini, A, et al.
Cancer Research, 47, 3239-3245 (1987)
View All Related Papers

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Advancing cancer research: From hallmarks & biomarkers to tumor microenvironment progression

"Recognizing both the tremendous opportunities and the challenges facing cancer research, we are dedicated to developing and refining tools and technologies for the study of cancer. With our comprehensive portfolio, including the Upstate®, Chemicon®, and Calbiochem® brands of reagents and antibodies, researchers can count on dependable, high quality solutions for analyzing all the hallmarks of cancer."

PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD
User Manual-ECM551
Cell Migration and Invasion: Choosing the Right Assay

Cell migration is stimulated and directed by interaction of cells with the extracellular matrix (ECM), neighboring cells, or chemoattractants. Cell migration participates in morphogenic processes, wound healing and tumor metastasis. Specifically, inhibiting tumor invasion by blocking tumor cell chemotaxis has been a major focus of research. Tumor cell invasion, marked by degradation of ECM, is also directly correlated with metastatic potential.

Global Trade Item Number

SKUGTIN
ECM55104053252626807

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