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Merck

MPTMAG-49K

MILLIPLEX® Mouse Pituitary Panel

Configurable Mouse Pituitary 7-Plex Panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Product Name

MILLIPLEX® Mouse Pituitary Panel, Configurable Mouse Pituitary 7-Plex Panel

species reactivity

mouse

manufacturer/tradename

Milliplex®

Quality Level

200

packaging

1 ea of

assay range

accuracy: 96-101%
standard curve range: 12.2-50,000 pg/mL
(TSH)
standard curve range: 122-500,000 pg/mL
(Prolactin)
standard curve range: 2.4-10,000 pg/mL
(ACTH)
standard curve range: 2.4-10,000 pg/mL
(BDNF)
standard curve range: 24.4-100,000 pg/mL
(FSH)
standard curve range: 4.9-20,000 pg/mL
(GH)
standard curve range: 4.9-20,000 pg/mL
(LH)
inter-assay cv: <20%
intra-assay cv: <15%

technique(s)

multiplexing: suitable

input

tissue/cellular lysate
plasma
culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in mouse serum, plasma, or cell/tissue culture supernatants.

Analytes Included: ACTH, BDNF, FSH, GH, LH, Prolactin, TSH

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Targets key pituitary hormones involved in endocrine and neuroendocrine regulation
  • Includes 7 analytes relevant to metabolism, growth, reproduction, and neuronal function
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with mouse serum, plasma, and cell/tissue culture supernatants
  • Designed for research in reproductive biology, endocrine disorders, and neuroendocrine signaling
Benefits:

  • Provides a comprehensive profile of pituitary hormone biomarkers in mouse models
  • Supports investigation of endocrine function and hormonal regulation mechanisms
  • Facilitates evaluation of therapeutic interventions and endocrine toxicity
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for preclinical and translational research

General description

The pituitary gland, often referred to as the “master gland,” regulates multiple endocrine functions through the secretion of key hormones. This panel—ACTH, BDNF, FSH, GH, LH, Prolactin, and TSH—captures essential indicators of adrenal, thyroid, gonadal, and neuroendocrine activity. The MILLIPLEX® Mouse Pituitary Panel enables multiplexed quantification of these biomarkers in mouse serum or plasma, supporting research in reproductive biology, metabolism, and endocrine disorders.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marina O Fernandez et al.
Endocrinology, 158(1), 121-133 (2016-11-15)
The peroxisome-proliferator activated receptor γ (PPARγ) is expressed in the hypothalamus in areas involved in energy homeostasis and glucose metabolism. In this study, we created a deletion of PPARγ brain-knockout (BKO) in mature neurons in female mice to investigate its
Tomohiro Terasaka et al.
Endocrinology, 160(8), 1999-2014 (2019-06-13)
Gonadotropin secretion, which is elicited by GnRH stimulation of the anterior pituitary gonadotropes, is a critical feature of reproductive control and the maintenance of fertility. In addition, activation of the GnRH receptor (GnRHR) regulates transcription and translation of multiple factors
An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.
Pitetti, JL; Calvel, P; Zimmermann, C; Conne, B; Papaioannou, MD; Aubry, F; Cederroth et al.
Molecular Endocrinology null
Thomas Blum et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(30), 15236-15243 (2019-07-10)
Dopamine neurons of the hypothalamic arcuate nucleus (ARC) tonically inhibit the release of the protein hormone prolactin from lactotropic cells in the anterior pituitary gland and thus play a central role in prolactin homeostasis of the body. Prolactin, in turn
Amanda Rodriguez et al.
Development (Cambridge, England), 146(23) (2019-11-11)
The number and quality of oocytes within the ovarian reserve largely determines fertility and reproductive lifespan in mammals. An oocyte-specific transcription factor cascade controls oocyte development, and some of these transcription factors, such as newborn ovary homeobox gene (NOBOX), are
View All Related Papers

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Global Trade Item Number

SKUGTIN
MPTMAG-49K-0704053252829055
MPTMAG-49K-0304053252829222
MPTMAG-49K-0404053252829024
MPTMAG-49K-0604053252829048
MPTMAG-49K-0104053252829208
MPTMAG-49K-0204053252829215
MPTMAG-49K-0504053252829031

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