Potassium phosphate monobasic

Name: Potassium phosphate monobasic
Brand: SIAL

tested according to Ph. Eur., anhydrous

Synonym(s):

Kalii dihydrogenophosphas, Potassium dihydrogen phosphate, prim.-Potassium phosphate

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About This Item

Linear Formula:

KH₂PO₄

CAS Number:

7778-77-0

Molecular Weight:

136.09

NACRES:

NA.25

PubChem Substance ID:

329758833

UNSPSC Code:

12161700

EC Number:

231-913-4

MDL number:

MFCD00011401

Product Name

Potassium phosphate monobasic, tested according to Ph. Eur., anhydrous

InChI key

GNSKLFRGEWLPPA-UHFFFAOYSA-M

InChI

1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

SMILES string

[K+].OP(O)([O-])=O

grade

anhydrous

Quality Level

200

agency

tested according to Ph. Eur.

assay

98-100.5% dry basis

form

crystalline

loss

<2.0% loss on drying

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

mp

252.6 °C (lit.)

solubility

water: 208 g/L at 20 °C

density

2.338 g/mL at 25 °C (lit.)

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Related Categories

Biochemicals

Biological Buffers

Phosphates

Application

Potassium phosphate monobasic buffer has been used as a component of the mobile phase in high-performance liquid chromatography (HPLC).

Biochem/physiol Actions

Potassium phosphate monobasic (MKP) is a commonly used buffering agent in biochemical and biological applications. It is used as a component of the buffer system in electrophoresis for the separation of biomolecules.

Features and Benefits

Assured high quality as it is tested according to both USP/NF and Ph. Eur. standards

General description

Potassium phosphate monobasic (KH₂PO₄), also known as monopotassium phosphate(MKP), is a soluble salt. It serves as a source of phosphorus and potassium. KH₂PO₄ is an essential component of potassium phosphate buffer, which is utilized in aqueous two-phase systems (ATPS) that are often used in the purification of lipases.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Vibrational spectroscopic studies (FTIR) of KDP, pure and doped with NH4Cl

Sheeba B, et al.

The Malaysian Journal of Analytical Sciences, 1255-1257 (2020)

In vitro studies: inhibition of nevirapine metabolism by nortriptyline in hepatic microsomes

Iris U and Esteban PJ

Bio-protocol, 5(19), e1607-e1607 (2015)

Novel aqueous two-phase systems based on tetrahydrofuran and potassium phosphate buffer for purification of lipase

L Ranyere S, et al.

Process Biochemistry (Oxford, United Kingdom), 50(9), 1459-1467 (2015)

Effect of buffer, electric field, and separation time on detection of aptamer-ligand complexes for affinity probe capillary electrophoresis

Buchanan DD, et al.

Electrophoresis, 24(9), 1375-1382 (2003)

LC method for the determination of oxcarbazepine in pharmaceutical preparations

Qi ML, et al.

Journal of Pharmaceutical and Biomedical Analysis, 31(1), 57-62 (2003)

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