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Merck

S6252

Sulfapyridine

≥99.0%

Synonym(s):

4-Amino-N-[2-pyridyl]benzene sulfonamide, N1-(Pyridin-2-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):
C11H11N3O2S
CAS Number:
144-83-2
Molecular Weight:
249.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329824561
EC Number:
205-642-7
Beilstein/REAXYS Number:
222065
MDL number:
MFCD00038036

Key Documents

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Product Name

Sulfapyridine, ≥99.0%

InChI

1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)

InChI key

GECHUMIMRBOMGK-UHFFFAOYSA-N

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2

assay

≥99.0%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfapyridine may be used as a reference standard in the determination of sulfapyridine in milk samples and plasma samples, using electrochemical magneto immunosensing assay technique and high performance liquid chromatography (HPLC), respectively.

General description

Sulfapyridine is a metabolite of Sulfasalazine. It is an antibiotic and is mostly used in treating rheumatoid arthritis.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361fd

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX2426
MKCX2427
MKCV3531
MKCT5896
MKCS2754

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Determination of sulfapyridine and its major metabolites in plasma by high-pressure liquid chromatography.
Fischer C and Klotz U.
Journal of Chromatography. B, Biomedical Sciences and Applications, 146(1), 157-162 (1978)
Electrochemical magneto immunosensing of antibiotic residues in milk.
Zacco E, et al.
Biosensors And Bioelectronics, 22(9-10), 2184-2191 (2007)
Christopher Chidley et al.
Nature chemical biology, 7(6), 375-383 (2011-04-19)
We introduce an approach for detection of drug-protein interactions that combines a new yeast three-hybrid screening for identification of interactions with affinity chromatography for their unambiguous validation. We applied the methodology to the profiling of clinically approved drugs, resulting in
Cemalettin Alp et al.
Journal of enzyme inhibition and medicinal chemistry, 27(6), 818-824 (2011-12-23)
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I, II and human serum isozyme VI, with a series of tosylited aromatic amine derivatives was investigated. The K(I) ranges of compounds 1-14 and acetazolamide against hCA I
Hai Haham et al.
Environmental science & technology, 46(21), 11870-11877 (2012-10-02)
Sorption-desorption behavior of sulfapyridine was studied with three distinct soil types low in organic carbon with or without the introduction of exogenous dissolved organic matter (DOM). Experiments with bulk soils yielded sorption coefficients equivalent to those obtained with soils richer
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