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04269

Sodium phosphate monobasic dihydrate

meets analytical specification of Ph. Eur., BP, USP, E 339, 98-100.5% (calc. to the dried substance)

Synonym(s):

Sodium dihydrogen phosphate dihydrate

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About This Item

Linear Formula:
NaH2PO4 · 2H2O
CAS Number:
13472-35-0
Molecular Weight:
156.01
PubChem Substance ID:
329747903
UNSPSC Code:
12161700
NACRES:
NA.25
EC Number:
231-449-2
MDL number:
MFCD00149209
Assay:
98-100.5% (calc. to the dried substance)
Form:
powder or crystals
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Quality Level

200

assay

98-100.5% (calc. to the dried substance)

form

powder or crystals

quality

meets analytical specification of Ph. Eur., BP, USP, E 339

impurities

heavy metals (as Pb), complies, organic volatile impurities, complies, reducing matter, complies, related substances, complies, residual solvents, complies, ≤0.2% water-insoluble matter

loss

21.5-24.0% loss on drying, 130 °C

pH

4.1-5.0 (20 °C, 1%), 4.2-4.5 (20 °C, 5%)

anion traces

chloride (Cl-): ≤50 mg/kg, fluoride (F-): ≤10 mg/kg, sulfate (SO42-): ≤200 mg/kg

cation traces

Al:, in accordance, As: ≤1 mg/kg, Ca: ≤20 mg/kg, Ca:, in accordance, Cd: ≤1 mg/kg, Cu: ≤10 mg/kg, Fe: ≤5 mg/kg, Hg: ≤1 mg/kg, Mg: ≤20 mg/kg, Pb: ≤4 mg/kg, Zn: ≤10 mg/kg

suitability

complies for appearance of solution

SMILES string

O.O.[Na+].OP(O)([O-])=O

InChI

1S/Na.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+1;;;/p-1

InChI key

VBJGJHBYWREJQD-UHFFFAOYSA-M

Application

Sodium phosphate monobasic dihydrate has been used for preparing phosphate buffer solution. It has also been used as a mobile phase for high-performance liquid chromatography.

Biochem/physiol Actions

Sodium phosphate monobasic also referred to as sodium dihydrogen phosphate is a chemical reagent possesses high buffering capacity and is used for preparing biological buffers. It was used as a phosphate supplement for determining whether phosphate supplementation can prevent rickets in very low birth weight infants with prenatal deficiency of phosphate.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP4225
BCCP4226
BCCN7797
BCCN7796
SDBB2649

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Funian Zhao et al.
Journal of chromatography. A, 1055(1-2), 109-114 (2004-11-25)
A method has been developed to analyze residual tetracyclines (TCs) (oxytetracycline (OTC), tetracycline (TC), chlortetracycline (CTC), methacycline (MTC), doxycycline (DC)) in ovine milk, using high-performance liquid chromatography (HPLC) with a coulometric electrode array system. The samples were pretreated, using liquid-liquid
P C Holland et al.
Lancet (London, England), 335(8691), 697-701 (1990-03-24)
A preliminary study showed that placental histology was abnormal for babies who subsequently had rickets. The findings--low plasma phosphate concentration; maximum percentage tubular reabsorption of phosphate; and high urinary calcium loss--are those of renal conservation of phosphate in the presence
Eva Bittrich et al.
Biointerphases, 5(4), 159-167 (2011-01-12)
With a coupled spectroscopic ellipsometry-quartz crystal microbalance with dissipation (QCM-D) experimental setup, quantitative information can be obtained about the amount of buffer components (water molecules and ions) coupled to a poly(acrylic acid) (PAA) brush surface in swelling and protein adsorption
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