201154

Sodium fluoride

Name: Sodium fluoride
Brand: SIGALD

ACS reagent, ≥99%

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About This Item

Linear Formula:

NaF

CAS Number:

7681-49-4

Molecular Weight:

41.99

NACRES:

NA.21

PubChem Substance ID:

329751974

UNSPSC Code:

12352302

EC Number:

231-667-8

MDL number:

MFCD00003524

assay:

≥99%

grade:

ACS reagent

form:

powder

Product Name

Sodium fluoride, ACS reagent, ≥99%

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

InChI

1S/FH.Na/h1H;/q;+1/p-1

SMILES string

[F-].[Na+]

grade

ACS reagent

agency

suitable for EPA 300

vapor pressure

1.4 mmHg ( 0 °C)

assay

≥99%

form

powder

impurities

≤0.01 meq/g Titr. base
≤0.02% insolubles
≤0.03 meq/g Titr. acid
≤0.1% sodium fluorosilicate

loss

≤0.3% loss on drying

mp

993 °C (lit.)

anion traces

chloride (Cl^-): ≤0.005%
sulfate (SO₄^2-): ≤0.03%
sulfite (SO₃^2-): ≤0.005%

cation traces

Fe: ≤0.003%
K: ≤0.02%
heavy metals (as Pb): ≤0.003%

Quality Level

200

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Lab Chemicals

Salts

Application

Sodium fluoride may be employed as a fluorination agent in the synthesis of aromatic and aliphatic fluorides. It may be used to prepare the lysis buffer.

Sodium fluoride may be used as a fluorinating agent for chlorine-containing compounds via halogen-exchange reaction.

Starting material for solid state preparation of Na₃MnF₆ for further high pressure structural determination studies.

General description

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed chemical preservative for the preservation of glucose in blood. It has been reported to stabilize the hepatic microsomal glucose-6-P phosphohydrolase enzyme.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

pictograms

GHS06

signalword

Danger

hcodes

H301,H315,H319

pcodes

P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

supp_hazards

EUH032

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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The effect on human dental caries of weekly oral rinsing with a sodium fluoride mouthwash: a final report.

Horowitz HS, et al.

Archives of Oral Biology, 16(6), 609-616 (1971)

A prospective, randomized clinical study on the effects of an amine fluoride/stannous fluoride toothpaste/mouthrinse on plaque, gingivitis and initial caries lesion development in orthodontic patients.

?gaard B, et al.

European Journal of Orthodontics, 28(1), 8-12 (2006)

Aluminum ions are required for stabilization and inhibition of hepatic microsomal glucose-6-phosphatase by sodium fluoride.

A J Lange et al.

The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)

Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of

The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl.

J G Drachman et al.

The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)

c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells

Carlson, S. et al.

Inorganic Chemistry, 37, 1486-1486 (1998)

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