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69293

Sucralose

≥98.0% (HPLC)

Synonym(s):

1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose

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About This Item

Empirical Formula (Hill Notation):
C12H19Cl3O8
CAS Number:
56038-13-2
Molecular Weight:
397.63
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
329761543
EC Number:
259-952-2
Beilstein/REAXYS Number:
3654410
MDL number:
MFCD03648615
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Quality Level

200

assay

≥98.0% (HPLC)

form

powder

optical activity

[α]/D 86.0±2.0°, c = 1 in H2O

sweetness

600 × sucrose

color

white to off-white

useful pH range

6-8 (20 °C, 100 g/L)

mp

114.5  °C ((238.1 °F ) - OECD Test Guideline 102)

solubility

~300 g/L at 25 °C (77 °F)

SMILES string

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

Application

LC-MS Analysis of Sucralose and Sucrose Octacetate on Ascentis RP-Amide
Sucralose is a non-caloric sugar used as a sweetener that activates T1R2/T1R3 sweet taste receptors and modulates glucagon-like peptide-1, glucose-dependent insulinotrophic peptide, and incretin secretion.

Biochem/physiol Actions

A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF8350V
BCCP6618
BCCN7504
0000487388
0000487388

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Nimesh Shukla et al.
Archives of biochemistry and biophysics, 639, 38-43 (2017-12-31)
Sucralose is a commonly employed artificial sweetener that appears to destabilize protein native structures. This is in direct contrast to the bio-preservative nature of its natural counterpart, sucrose, which enhances the stability of biomolecules against environmental stress. We have further
Christopher B Forsyth et al.
PloS one, 6(12), e28032-e28032 (2011-12-07)
Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging. The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main component is alpha-synuclein protein. The finding of these Lewy bodies in the intestinal enteric nerves
Virender K Sharma et al.
Chemosphere, 87(6), 644-648 (2012-02-22)
The kinetics of the oxidation of sucralose, an emerging contaminant, and related monosaccharides and disaccharides by ferrate(VI) (Fe(VI)) were studied as a function of pH (6.5-10.1) at 25°C. Reducing sugars (glucose, fructose, and maltose) reacted faster with Fe(VI) than did
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