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Merck

74284

Luteolin 7-O-β-D-glucoside

≥98.0% (HPLC)

Synonym(s):

3′,4′,5,7-Tetrahydroxyflavone 7-glucoside, Cynaroside, Glucoluteolin, Glucosylluteolin, Luteoloside

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About This Item

Empirical Formula (Hill Notation):
C21H20O11
CAS Number:
5373-11-5
Molecular Weight:
448.38
NACRES:
NA.28
PubChem Substance ID:
329765596
UNSPSC Code:
12352202
EC Number:
226-365-8
MDL number:
MFCD06799436

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InChI

1S/C21H20O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-6,16,18-25,27-29H,7H2/t16-,18-,19+,20-,21-/m1/s1

InChI key

PEFNSGRTCBGNAN-QNDFHXLGSA-N

SMILES string

OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C=C(Oc3c2)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O

assay

≥98.0% (HPLC)

form

powder or crystals

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

Quality Level

100

Related Categories

General description

Luteolin 7-O-β-D-glucoside (LUT-7G) is a flavonoid recently isolated from the Bidens parviflora Wild plant. It is a glycosylated form of luteolin present in many plants.

Biochem/physiol Actions

Luteolin 7-O-β-D-glucoside possesses antioxidant, antiviral, and antibacterial properties. It is a hexokinase 2 (HEK2) inhibitor with anti-inflammatory and anti-proliferative activities. LUT-7G also exerts cardioprotective effects against H9c2 cells injury induced by oxidative stress.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF4330V
WXBF0850V
WXBD6964V
WXBD4430V
WXBD1730V

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Ramona Palombo et al.
International journal of molecular sciences, 20(11) (2019-06-05)
Flavonoids have been demonstrated to affect the activity of many mammalian enzyme systems. Their functional phenolic groups are able to mediate antioxidant effects by scavenging free radicals. Molecules of this class have been found able to modulate the activity of
Meng-Na Wang et al.
Natural product research, 1-6 (2021-01-13)
A new flavonoid, saffloflavone , along with six known compounds, kaempferol-3-O-rutinoside, kaempferol-3-O-sophoroside, quercetin-3-O-β-d-glucoside, quercetin-7-O-β-d-glucoside, luteolin-7-O-β-d-glucoside and kaempferol 3-O-β-d-glucoside were isolated from the flowers of Carthamus tinctorius L. All the structures were determined by interpretation of their spectroscopic data. The cardioprotective
Yu-Lan Li et al.
Molecules (Basel, Switzerland), 13(8), 1931-1941 (2008-09-17)
Fifteen flavonoids, 1-7 and 9-16, and a polyacetylene, 8, were isolated from the ethanol extract of the dried whole plant of Bidens parviflora Willd. by various chromatographic techniques. Their structures have been elucidated on the basis of spectroscopic analyses and
Donatella Negro et al.
Journal of food science, 77(2), C244-C252 (2012-01-19)
Polyphenol compounds, particularly caffeoylquinic acids and flavonoids, were measured in different tissues and developmental stages of 6 artichoke varietal types diffused in the Mediterranean region. Flower heads were subdivided into external, intermediate, internal bracts, and receptacle, while leaves were collected
Meihua Jin et al.
Biological & pharmaceutical bulletin, 32(9), 1500-1503 (2009-09-02)
Previously, we reported that an ethanol extract of Ailanthus altissima has antiinflammatory activity in an ovalbumin (OVA)-sensitized murine asthmatic model. To determine the biological compounds from this plant, luteolin-7-O-glucoside (L7G) was isolated and its antiasthmatic activity was evaluated in an
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