A7003
Alginic acid from brown algae
powder
Synonym(s):
Alginic acid from Macrocystis pyrifera (kelp), Mixed polymer of mannuronic and guluronic acid
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About This Item
Linear Formula:
(C6H8O6)n
CAS Number:
UNSPSC Code:
12171500
EC Number:
232-680-1
NACRES:
NA.47
MDL number:
Product Name
Alginic acid from brown algae, powder
form
powder
technique(s)
titration: suitable
color
white to light yellow
pH range
1.5-3.5
mp
300 °C
solubility
H2O: insoluble, but swells
aqueous base: soluble
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
Alginic acid is suitable reagent used to study the in-vitro and in-vivo mitogenic activity of alginates. It is suitable for use in the spectrophotometric determination of transparent exopolymer particles by dye-binding assay.
General description
Alginic acid is a high molecular weight linear polymer isolated from seaweed. It is a linear β-1→4-linked polymer of n-mannuronic and L-guluronic acid. It is an acid polysaccharide present in the extracellular matrix of brown algae. It is reported to inhibit the reverse transcriptase activity of HIV. Structural investigation of alginic acid, a marine algal polysaccharide poly-α-L-guluronic acid, has been reported. Anti-inflammatory effect of alginic acid, isolated from the brown algae Sargassum wightii, in type II collagen induced arthritic rats has been reported. Pyrolysis of alginic acid using py-GC/MS over a wide temperature range (200-800°C) and thermogravimetric analysis (TGA) has been reported. It was reported to cause the biocorrosion of thin films of copper on germanium internal reflection elements (IREs).
Other Notes
A straight-chain, hydrophilic, colloidal, polyuronic acid composed primarily of anhydro-β-D-mannuronic acid residues with 1→4 linkage.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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G Klöck et al.
Applied microbiology and biotechnology, 40(5), 638-643 (1994-01-01)
Alginate is used as a matrix for immunoisolation of cells and tissues in vivo. We have demonstrated previously that commercial alginates contain various fractions of mitogenic impurities and that they can be removed by free flow electrophoresis. The use of
K C S Queiroz et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(5), 303-307 (2008-05-06)
Brown algae have two kinds of acid polysaccharides present in the extracellular matrix: sulfated fucan and alginic acid. We have previously isolated and characterized fucans from several species of brown seaweed. The characterized fucans from Dictyotaceae are heterofucans containing mainly
In situ, real-time FT-IR/CIR/ATR study of the biocorrosion of copper by gum arabic, alginic acid, bacterial culture supernatant and Pseudomonas atlantica exopolymer.
Jolley JG, et al.
Applied Spectroscopy, 43(6), 1062-1067 (1989)
C H Sarithakumari et al.
International immunopharmacology, 17(4), 1108-1115 (2014-01-22)
The present study evaluated the anti-inflammatory potential of alginic acid isolated from the brown algae Sargassum wightii in type II collagen induced arthritic rats, a well established arthritic model that resembles more closely to human rheumatoid arthritis in its clinical
Structural components of alginic acid. II. The crystalline structure of poly-alpha-L-guluronic acid. Results of x-ray diffraction and polarized infrared studies.
E D Atkins et al.
Biopolymers, 12(8), 1879-1887 (1973-01-01)
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