A8056

3-Amino-1,2,4-triazole

Name: 3-Amino-1,2,4-triazole
Brand: SIGMA

powder, ≥95% (TLC)

Synonym(s):

1,2,4-Triazol-3-amine, 3-AT, Amitrol

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All Photos(2)

About This Item

Empirical Formula (Hill Notation):

C₂H₄N₄

CAS Number:

61-82-5

Molecular Weight:

84.08

NACRES:

NA.83

PubChem Substance ID:

24891312

UNSPSC Code:

12352204

EC Number:

200-521-5

MDL number:

MFCD00005230

Beilstein/REAXYS Number:

107687

Product Name

3-Amino-1,2,4-triazole, ≥95% (TLC)

InChI

1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)

SMILES string

Nc1nc[nH]n1

InChI key

KLSJWNVTNUYHDU-UHFFFAOYSA-N

biological source

synthetic (organic)

assay

≥95% (TLC)

form

powder

potency

30 μM K_i

mp

150-153 °C (lit.)

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

−20°C

Quality Level

200

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Application

3-Amino-1,2,4-triazole has been used:

as an organelle-specific perturbant in human embryonic kidney (HEK293T) cells
as histidine biosynthesis inhibitor in medium for screening co-transformants from yeast two-hybrid interactions
for preservation of midgut sample from honey bee
for the determination of tryptophan in proteins.

General description

3-Amino-1,2,4-triazole is a herbicide effective against weeds especially bermuda and quack grass. It enters plant circulation through roots and is majorly present in the meristem. 3-Amino-1,2,4-triazole inhibits chlorophyll synthesis resulting in chlorotic leaves and albino plants. In addition, it also affects the growth of the plants. It is exploited to destroy unwanted weeds. It is synthesized from aminoguanidine formate and corresponds to a molecular weight of 84 Da.

pictograms

GHS08,GHS09

signalword

Warning

hcodes

H361d,H373,H411

pcodes

P202 - P260 - P273 - P280 - P308 + P313 - P391

Hazard Classifications

Aquatic Chronic 2 - Repr. 2 - STOT RE 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Bipartite anchoring of SCREAM enforces stomatal initiation by coupling MAP kinases to SPEECHLESS.

Aarthi Putarjunan et al.

Nature plants, 5(7), 742-754 (2019-06-27)

Cell fate in eukaryotes is controlled by mitogen-activated protein kinases (MAPKs) that translate external cues into cellular responses. In plants, two MAPKs-MPK3 and MPK6-regulate diverse processes of development, environmental response and immunity. However, the mechanism that bridges these shared signalling

The Biology and Control of Weeds in Sugarcane, 88-88 (2012)

Understanding organellar protein folding capacities and assessing their pharmacological modulation by small molecules

Sharma R, et al.

European Journal of Cell Biology, 97(2), 114-125 (2018)

Thermoanalytical study of the pesticide 3-amino-1, 2, 4-triazole

Sanchez-Soto P, et al.

Journal of Thermal Analysis and Calorimetry, 45(5), 1189-1197 (1995)

Nt-RhoGDI2 regulates Rac/Rop signaling and polar cell growth in tobacco pollen tubes

Klahre U, et al.

The Plant Journal, 46(6), 1018-1031 (2006)

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