C1506

Cytidine 5′-triphosphate disodium salt

Name: Cytidine 5′-triphosphate disodium salt
Brand: SIGMA

≥95%, P2X4 purinergic receptor agonist, powder

Synonym(s):

CTP

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₄N₃Na₂O₁₄P₃

CAS Number:

36051-68-0

Molecular Weight:

527.12

NACRES:

NA.77

PubChem Substance ID:

24892417

UNSPSC Code:

41106305

EC Number:

252-849-3

MDL number:

MFCD00078193

Product Name

Cytidine 5′-triphosphate disodium salt, ≥95%

InChI key

NFQMDTRPCFJJND-WFIJOQBCSA-L

InChI

1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

SMILES string

[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O

assay

≥95%

form

powder

storage temp.

−20°C

Quality Level

200

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Related Categories

Bioactive Small Molecule Agonists

Bioactive Small Molecules

Phosphates

Application

Cytidine 5′-triphosphate disodium salt has been used:

for the conversion of adenosine monophosphate (AMP) to adenosine diphosphate (ADP) in luminometry analysis
in the preparation of ribonucleotide 5′-triphosphate precursors stocks for large-scale RNA synthesis
to perform in vitro transcription

Biochem/physiol Actions

Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis. Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.

P2X₄ purinergic receptor agonist.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Secretion From Dense Granules

Platelets and megakaryocytes, 83-93 (2004)

Methods in Molecular Biology, 89-89 (2018)

Genetics (2016)

Scientific and Technical Terms in Bioengineering and Biological Engineering (2018)

Purification and characterization of transcribed RNAs using gel filtration chromatography.

Sean A McKenna et al.

Nature protocols, 2(12), 3270-3277 (2007-12-15)

RNA synthesis using in vitro transcription by phage T7 RNA polymerase allows preparation of milligram quantities of RNA for biochemical, biophysical and structural investigations. Previous purification approaches relied on gel electrophoretic or gravity-flow chromatography methods. We present here a protocol

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