C3416

Carbenicillin disodium salt

Name: Carbenicillin disodium salt
Brand: SIGMA

BioReagent, suitable for plant cell culture

Synonym(s):

α-Carboxybenzylpenicillin disodium salt

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₁₆N₂Na₂O₆S

CAS Number:

4800-94-6

Molecular Weight:

422.36

UNSPSC Code:

51282413

NACRES:

NA.76

PubChem Substance ID:

24892613

EC Number:

225-360-8

Beilstein/REAXYS Number:

5722128

MDL number:

MFCD00077683

Product Name

Carbenicillin disodium salt, BioReagent, suitable for plant cell culture

InChI key

RTYJTGSCYUUYAL-YCAHSCEMSA-L

InChI

1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1

SMILES string

[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O

product line

BioReagent

form

powder

technique(s)

cell culture | plant: suitable

solubility

H₂O: 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

agriculture

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

Quality Level

200

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Related Categories

Antibiotics

Biochemicals

Cell Culture & Analysis

Cell Culture Media & Buffers

Cell Culture Supplements & Reagents

Analysis Note

Stable at 37 °C for 3 days

Application

Recommended for antibacterial use in cell culture media at 100 μg/ml and for selection of ampr transformed cells.

Biochem/physiol Actions

Mode of Action: Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.

Antimicrobial spectrum: Active against Gram-positive and Gram-negative bacteria

General description

Chemical structure: ß-lactam

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

Physical form

Hygroscopic powder

pictograms

GHS08

signalword

Danger

hcodes

H317,H334

pcodes

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

0000504448

0000480607

0000480606

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Assembly of hybrid bacteriophage Qbeta virus-like particles.

Steven D Brown et al.

Biochemistry, 48(47), 11155-11157 (2009-10-24)

Bacteriophage Qbeta coat protein forms uniform virus-like particles when expressed recombinantly in a variety of organisms. We have inserted the IgG-binding Z domain at the carboxy terminus of the coat protein and coexpressed this chimeric subunit with native coat protein

Outbreak due to a Klebsiella pneumoniae strain harbouring KPC-2 and VIM-1 in a German university hospital, July 2010 to January 2011.

J Steinmann et al.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 16(33) (2011-08-30)

We describe the epidemiology and characteristics of the pathogen and patients (n=7) associated with an outbreak of a carbapenem-resistant Klebsiella pneumoniae (CRKP) strain in a German university hospital from July 2010 to January 2011. Species identification and detection of carbapenem

Reverting antibiotic tolerance of Pseudomonas aeruginosa PAO1 persister cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one.

Jiachuan Pan et al.

PloS one, 7(9), e45778-e45778 (2012-10-03)

Bacteria are well known to form dormant persister cells that are tolerant to most antibiotics. Such intrinsic tolerance also facilitates the development of multidrug resistance through acquired mechanisms. Thus persister cells are a promising target for developing more effective methods

Developmental expression of non-coding RNAs in Chlamydia trachomatis during normal and persistent growth.

Yasser M Abdelrahman et al.

Nucleic acids research, 39(5), 1843-1854 (2010-11-06)

Chlamydia trachomatis is an obligate intracellular bacterium that exhibits a unique biphasic developmental cycle that can be disrupted by growth in the presence of IFN-γ and β-lactams, giving rise to an abnormal growth state termed persistence. Here we have examined

Efficient embryogenic suspension culturing and rapid transformation of a range of elite genotypes of sweet potato (Ipomoea batatas [L.] Lam.).

Jun Yang et al.

Plant science : an international journal of experimental plant biology, 181(6), 701-711 (2011-10-01)

Efficient Agrobacterium tumefaciens-mediated transformation was developed using embryogenic suspension cell cultures of elite sweet potato (Ipomoea batatas [L.] Lam.) cultivars, including Ayamurasaki, Sushu2, Sushu9, Sushu11, Wanshu1, Xushu18 and Xushu22. Embryogenic suspension cultures were established in LCP medium using embryogenic calli

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