C5132
Carbazole
≥95% purity (GC), powder
Synonym(s):
Dibenzopyrrole; Diphenylenimine
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About This Item
Empirical Formula (Hill Notation):
C12H9N
CAS Number:
Molecular Weight:
167.21
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
201-696-0
MDL number:
Beilstein/REAXYS Number:
3956
Product Name
Carbazole, ≥95% (GC)
vapor pressure
400 mmHg ( 323 °C)
Quality Level
assay
≥95% (GC)
form
powder
technique(s)
titration: suitable
color
white to tan
bp
355 °C (lit.)
mp
243-246 °C (lit.)
solubility
acetone: 50 mg/mL
density
1.1 g/cm3 at 18 °C
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
c1ccc2c(c1)[nH]c3ccccc23
InChI
1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H
InChI key
UJOBWOGCFQCDNV-UHFFFAOYSA-N
General description
Carbazole is an aromatic heterocyclic organic molecule.
Application
Carbazole has been used in the uronic acid assay.
Biochem/physiol Actions
Carbazole mainly interacts with DNA and damages it. These events suppress the synthesis of new DNA or RNA. Carbazole derivatives are involved in antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidant, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective, and pancreatic lipase suppression activities.
Analysis Note
May contain dark particles.
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 4 - Carc. 2 - Muta. 2
Storage Class
11 - Combustible Solids
flash_point_f
428.0 °F - closed cup
flash_point_c
220.0 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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A complete set of hyaluronan fragments obtained from hydrolysis catalyzed by hyaluronidase: Application to studies of hyaluronan mass distribution by simple HPLC devices.
Tranchepain F, et al.
Analytical Biochemistry, 348, 232-242 (2006)
CARBAZOLE DERIVATIVES IN CANCER TREATMENT-A REVIEW.
Kanneti Naga M, et al.
World Journal of Pharmacy and Pharmaceutical Sciences (2015)
Shen H Tan et al.
Organic letters, 14(22), 5621-5623 (2012-10-31)
The racemic modification of the Aspidosperma alkaloid limaspermidine (1) has been prepared in ten steps including one involving a Raney-cobalt-mediated tandem reductive cyclization of nitrile 8 to give the tetracyclic system 9b. Compound (±)-1 has been converted over two steps