C6734
CAY10397
solid, >98%
Synonym(s):
5-[[4-(Ethoxycarbonyl)phenyl]azo]-2-hydroxybenzeneacetic acid, CK47A
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About This Item
Empirical Formula (Hill Notation):
C17H16N2O5
CAS Number:
Molecular Weight:
328.32
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Product Name
CAY10397, >98%, solid
SMILES string
CCOC(=O)c1ccc(cc1)\N=N\c2ccc(O)c(CC(O)=O)c2
InChI
1S/C17H16N2O5/c1-2-24-17(23)11-3-5-13(6-4-11)18-19-14-7-8-15(20)12(9-14)10-16(21)22/h3-9,20H,2,10H2,1H3,(H,21,22)/b19-18+
InChI key
YYBSDOZYJSGLTH-VHEBQXMUSA-N
assay
>98%
form
solid
shipped in
wet ice
storage temp.
−20°C
Quality Level
Related Categories
Biochem/physiol Actions
Potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy-PGDH). Acts to prolong the lifetime and activity of endogenously produced prostaglandins both in vitro and in vivo.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Shaneice K Nettleford et al.
Frontiers in nutrition, 7, 96-96 (2020-08-11)
Enteropathogenic Escherichia coli (EPEC) leads to adverse colonic inflammation associated with poor resolution of inflammation and loss of epithelial integrity. Micronutrient trace element selenium (Se) is incorporated into selenoproteins as the 21st amino acid, selenocysteine (Sec). Previous studies have shown
Christian Hunnicke Petersen et al.
BMC cancer, 19(1), 643-643 (2019-06-30)
Investigations of colorectal carcinogenesis have mainly focused on examining neoplastic tissue. With our aim of identifying potentially cancer-predisposing molecular compositions, we chose a different approach by examining endoscopically normal appearing colonic mucosa of patients with and without colorectal neoplasia (CRN).
Liuping Wei et al.
Cellular signalling, 26(7), 1476-1488 (2014-03-25)
We have established that 15-hydroxyeicosatetraenoic acid is an important factor in regulation of pulmonary vascular remodeling (PVR) associated with hypoxia-induced pulmonary hypertension (PH), which is further metabolized by 15-hydroxyprostaglandin dehydrogenase (15-PGDH) to form 15-ketoeicosatetraenoic acid (15-KETE). However, the role of
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