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Merck

D3664

Deoxyribonucleic acid sodium salt from calf thymus

suitable for substrate for DNase (Readily soluble)

Synonym(s):

CT-DNA, calf thymus DNA, DNA sodium salt from calf thymus, Thymonucleic acid sodium salt

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About This Item

CAS Number:
UNSPSC Code:
41106305
eCl@ss:
32160414
NACRES:
NA.51
MDL number:
Form:
powder or crystals
Storage temp.:
2-8°C
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form

powder or crystals

Quality Level

suitability

suitable for substrate for DNase (Readily soluble)

storage temp.

2-8°C

Application

Calf thymus DNA (CT-DNA) is a natural DNA widely used in studies of DNA binding anticancer agents and DNA binding agents that modulate DNA structure and function. Calf thymus DNA is also used in physicochemical studies of DNA behavior in solution.

Packaging

Preweighed vials prepared from D1501


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Protocols

To standardize a procedure for the enzymatic assay of Deoxyribonuclease I.

Related Content

Product Information Sheet


Abdollah Zakeri Siavashani et al.
Biomaterials science, 8(1), 148-162 (2019-10-31)
Implantation of temporary and permanent biomaterials in the body leads to a foreign body reaction (FBR), which may adversely affect tissue repair processes and functional integration of the biomaterial. However, modulation of the inflammatory response towards biomaterials can potentially enable
Kristin Grøsvik et al.
Frontiers in microbiology, 11, 263-263 (2020-03-12)
The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine (m3A), which in Escherichia coli is removed by m3A-DNA glycosylase I (Tag) and II
Claire L Camp et al.
Analytical and bioanalytical chemistry, 402(1), 367-372 (2011-08-31)
The determination of total deoxyribonucleic acid (DNA) concentration is of great importance in many biological and bio-medical analyses. The quantification of DNA is traditionally performed by UV spectroscopy; however the results can be affected greatly by the sample matrix. The