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Merck

F9130

Furaltadone

Synonym(s):

5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidinone

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O6
CAS Number:
139-91-3
Molecular Weight:
324.29
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
24894989
EC Number:
205-384-5
Beilstein/REAXYS Number:
8130725
MDL number:
MFCD00057356

InChI key

YVQVOQKFMFRVGR-VGOFMYFVSA-N

InChI

1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+

SMILES string

[O-][N+](=O)c1ccc(\C=N\N2CC(CN3CCOCC3)OC2=O)o1

storage temp.

2-8°C

Quality Level

200

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Application

Furaltadone has been used as a reference standard in liquid chromatography-mass spectrometry (LC-MS/MS) quantifying nitrofuran metabolites in aquaculture matrixes and honey.

Biochem/physiol Actions

Nitrofurans are commercially used as feed additives to promote growth in various fields such as aquaculture, bee colonies, and livestock.

General description

Furaltadone is a nitrofuran containing a 5-nitrofuran ring and is a member of synthetic antibiotics.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
017H1158
035F0119

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Nitrofuran antibiotics: a review on the application, prohibition and residual analysis
Vass M, et al.
Veterinary medicine (Auckland, N.Z.), 53(9), 469-469 (2008)
Brian T Veach et al.
Journal of AOAC International, 101(3), 897-904 (2017-12-01)
This paper describes a rapid and robust method utilizing a single liquid-liquid extraction for the quantitation and confirmation of chloramphenicol, florfenicol, and nitrofuran metabolites in honey. This methodology combines two previous extraction methods into a single extraction procedure and utilizes
Sara Leston et al.
Chemosphere, 82(7), 1010-1016 (2010-11-27)
The use of pharmaceuticals in the food production industry as prophylatic and therapeutic agents is necessary to promote animal health, but may entail significant consequences to natural ecosystems, especially in the cases of overdosing and use of banned pharmaceuticals. The
Hiroshige Mikamo et al.
The Japanese journal of antibiotics, 59(6), 468-473 (2007-03-06)
We investigated the efficacies of various administration methods for levofloxacin (LVFX) and tosufloxacin (TFLX) against 161 isolates of Streptococcus pneumoniae and 309 isolates of Haemophilus influenzae isolated in Gifu prefecture, using Monte Carlo simulation. The pharmacokinetic parameters of the fluoroquinolones
Zhen-Lin Xu et al.
Talanta, 103, 306-313 (2012-12-04)
A heterologous competitive indirect enzyme-linked immunosorbent assay (ciELISA) for the determination of the furaltadone metabolite 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ) was developed. AMOZ was derivatised with 2-(4-formylphenoxy) acetic acid or 2-(3-formylphenoxy) acetic acid to obtain two novel immunizing haptens. The ability of these
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