Product Name
Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes, lyophilized powder, 50-150 units/mg protein
form
lyophilized powder
specific activity
50-150 units/mg protein
composition
Protein, 40-70% biuret
UniProt accession no.
foreign activity
3-Phosphoglyceric phosphokinase ≤2%
storage temp.
−20°C
Quality Level
Gene Information
human ... GAPDH(2597)
Related Categories
Biochem/physiol Actions
Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.
Other Notes
One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.
Physical form
Lyophilized powder containing sodium citrate buffer salts
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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C Fossum et al.
Veterinary immunology and immunopathology, 150(3-4), 141-148 (2012-10-06)
The expression of tlr4, md2 and cd14 was studied in equine blood leukocytes and in intestinal samples using real time PCR. The stability of three commonly used reference genes, glyceraldehyde-3P-dehydrogenase (GAPDH), hypoxantine ribosyltransferase (HPRT) and succinate dehydrogenase complex subunit A
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Proceedings of the National Academy of Sciences of the United States of America, 109(33), 13308-13313 (2012-08-01)
Oxidative stress regulates telomere homeostasis and cellular aging by unclear mechanisms. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a key mediator of many oxidative stress responses, involving GAPDH nuclear translocation and induction of cell death. We report here that GAPDH interacts with
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