H3663

Anti-HA antibody, Mouse monoclonal

Name: Anti-HA antibody, Mouse monoclonal
Brand: SIGMA

clone HA-7, purified from hybridoma cell culture

Synonym(s):

Monoclonal Anti-HA, Anti-HA, Anti-Influenza Hemagglutinin

Select a Size

All Photos(4)

About This Item

UNSPSC Code:

12352203

NACRES:

NA.56

MDL number:

MFCD00803873

Product Name

Anti-HA antibody, Mouse monoclonal, clone HA-7, purified from hybridoma cell culture

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

HA-7, monoclonal

concentration

~1 mg/mL

technique(s)

immunocytochemistry: 1.0-2.0 μg/mL
immunoprecipitation (IP): 0.5-2.0 μg
western blot: 0.25-1 μg/mL

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Application

Monoclonal Anti-HA antibody produced in mouse has been used:

in immunoblotting
in immunocytochemistry
in the immunoprecipitation

Biochem/physiol Actions

Hemagglutinin (HA) binds to acid binding and is essential for the initiation of virus infection. It is the key target for the generation of vaccine. HA is the dominant antigen against which humoral immune response is provoked. Vaccines development involves the generation of antibody specific to the variable head and the conserved stalk region. Both the anti-stalk and anti-head antibodies may elicit protective function in influenza disease.

The antibody recognizes native as well as denatured-reduced forms of HA-tagged proteins and is reactive with N- or C-terminal HA-tagged fusion proteins expressed in E. coli or in mammalian cells.

General description

Hemagglutinin (HA) is a glycoprotein present in the membrane of influenza virus. HA exists as a trimer and each monomer at its membrane tip has receptor-binding site. Glycosylation event of HA occurs in endoplasmic reticulum. The head region with the receptor-binding site of the HA is variable. The mouse monoclonal Anti-HA, Clone HA-7 recognizes the human influenza virus hemagglutinin (HA), known as the HA tag. The product is reactive with HA-tagged fusion proteins expressed at either the amino or the carboxy terminus of the fusion protein.

Immunogen

synthetic peptide corresponding to a fragment of human influenza virus hemagglutinin (HA) known as HA-tag, conjugated to KLH

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide as a preservative.

Not finding the right product?

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000485143

0000430838

0000400114

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade.

Yumei Zheng et al.

Nature communications, 10(1), 3600-3600 (2019-08-11)

Autophagy depends on the E2 enzyme, Atg3, functioning in a conserved E1-E2-E3 trienzyme cascade that catalyzes lipidation of Atg8-family ubiquitin-like proteins (UBLs). Molecular mechanisms underlying Atg8 lipidation remain poorly understood despite association of Atg3, the E1 Atg7, and the composite

A newly cloned ClC-3 isoform, ClC-3d, as well as ClC-3a mediates Cd2+-sensitive outwardly rectifying anion currents

Okada T, et al.

Cellular Physiology and Biochemistry, 33(3), 539-556 (2014)

Influenza hemagglutinin and neuraminidase membrane glycoproteins

Gamblin SJ and Skehel JJ

The Journal of Biological Chemistry, 285(37), 28403-28409 (2010)

Evaluation of pre-existing anti-hemagglutinin stalk antibody as a correlate of protection in a healthy volunteer challenge with influenza A/H1N1pdm virus

Park JK, et al.

mBio, 9(1), e02284-e02217 (2018)

Ribosomal protein L4 interacts with viral protein VP3 and regulates the replication of infectious bursal disease virus

Chen Y, et al.

Virus Research, 211, 73-78 (2016)

View All Related Papers