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Merck

I1010

IgA from human colostrum

reagent grade, ≥95%, essentially salt-free, lyophilized powder

Synonym(s):

Human IgA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
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Product Name

IgA from human colostrum, reagent grade, ≥95%, essentially salt-free, lyophilized powder

conjugate

unconjugated

grade

reagent grade

assay

≥95%

form

essentially salt-free, lyophilized powder

storage temp.

2-8°C

Quality Level

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Application

Purified IgA may be used as a reference antigen, standard, blocking agent or coating protein in a variety of immunoassays including ELISA, dot immunobinding, immunoblotting, immunodiffusion and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solidphase immunoadsorbents. IgA from human colostrum was used as a standard in ELISA (1 mg/ml) and gel electrophoresis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears, colostrum and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Human IgA is purified from pooled normal human colostrum by fractionation and ion-exchange fractionation.

Preparation Note

Reconstitute with buffered saline (150 mM sodium chloride).

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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P Kosuwon et al.
Beneficial microbes, 9(4), 541-552 (2018-04-11)
Little is known about the impact of nutrition on toddler gut microbiota. The plasticity of the toddler gut microbiota indicates that nutritional modulation beyond infancy could potentially impact its maturation. The objective of this study was to determine the effect
Hannah Karen Mina Labayo et al.
EClinicalMedicine, 27, 100561-100561 (2020-10-13)
Norovirus (NV) causes acute gastroenteritis in infants. Humoral and fecal immunoglobulin A (IgA) responses have been correlated with protection against NV; however, the role of breast milk IgA against NV infection and associated diarrhea is still unknown. This study aimed
E Knop et al.
Investigative ophthalmology & visual science, 42(3), 566-574 (2001-02-27)
Mucosa-associated lymphoid tissue (MALT) specifically protects mucosal surfaces. In a previous study of the human conjunctiva, evidence was also found for the presence of MALT in the lacrimal sac. The present study, therefore, aims to investigate its morphology and topographical
Lauri Vehkala et al.
Annals of medicine, 45(8), 501-510 (2013-10-18)
Obesity and type 2 diabetes (T2D) associate with increased oxidative stress. Malondialdehyde acetaldehyde (MAA) adducts have been suggested to be one of the antigenic epitopes in MDA-LDL responsible for the antibody recognition. Our aim was to investigate the associations between
Nguyen V Trang et al.
Human vaccines & immunotherapeutics, 10(12), 3681-3687 (2015-02-11)
Rotavirus (RV) is the most common cause of childhood diarrhea worldwide, and several vaccines have been successfully developed to reduce the burden of disease. However, lower vaccine immunogenicity and efficacy in developing countries might be related to the virus-neutralizing activity

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