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Merck

L1516

Lectin from Wisteria floribunda

buffered aqueous solution, biotin conjugate

Synonym(s):

Wisteria floribunda agglutinin, WFA

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
MFCD00166187

Product Name

Lectin from Wisteria floribunda, buffered aqueous solution, biotin conjugate

conjugate

biotin conjugate

form

buffered aqueous solution

packaging

pkg of 2 mg active conjugate

storage temp.

2-8°C

Quality Level

200

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Analysis Note

Agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, of a 1 mg/ml solution. This activity is the lowest concentration to agglutinate a 2% suspension of human blood group A erythrocytes after 1 hr incubation at 25 °C.

Biochem/physiol Actions

WFA is not blood group specific, but has an affinity for N-acetyl-D-galactosamine.

Packaging

Package size based on active conjugate content

Preparation Note

Protein is biotinylated utilizing aminocaproyl spacer.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000508497
0000508497
0000505214
0000505214
0000498033

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Vision loss has long since been considered irreversible after a critical period; however, there is potential to restore limited vision, even in adulthood. This phenomenon is particularly pronounced following complete loss of vision in the dominant eye. Adult neural cell
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NETO2 is an auxiliary subunit for kainate-type glutamate receptors that mediate normal cued fear expression and extinction. Since the amygdala is critical for these functions, we asked whether Neto2 -/- mice have compromised amygdala function. We measured the abundance of
Vanessa Cattaud et al.
Neurobiology of aging, 72, 147-158 (2018-10-03)
Recent findings show that parvalbumin (PV) interneuron function is impaired in Alzheimer's disease (AD), and that this impairment in PV function can be linked to network dysfunction and memory deficits. PV cells are often associated with a specific extracellular matrix
Kelly E Carstens et al.
The European journal of neuroscience, 53(12), 4005-4015 (2020-11-22)
Current methods of experimentally degrading the specialized extracellular matrix (ECM), perineuronal nets (PNNs) have several limitations. Genetic knockout of ECM components typically has only partial effects on PNNs, and knockout of the major ECM component aggrecan is lethal in mice.
Carly M Drzewiecki et al.
Brain structure & function, 225(8), 2495-2507 (2020-09-12)
The prefrontal cortex (PFC) is a late developing region of the cortex, and its protracted maturation during adolescence may confer a period of plasticity. Closure of critical, or sensitive, periods in sensory cortices coincides with perineuronal net (PNN) expression, leading
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