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Merck

L4263

Sodium DL-lactate solution

syrup, BioReagent, 60 % (w/w), synthetic, suitable for cell culture

Synonym(s):

DL-Lactic acid sodium salt

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About This Item

Linear Formula:
CH3CH(OH)COONa
CAS Number:
72-17-3
Molecular Weight:
112.06
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
24896366
EC Number:
200-772-0
Beilstein/REAXYS Number:
4332999
MDL number:
MFCD00065400

Product Name

Sodium DL-lactate solution, syrup, BioReagent, 60 % (w/w), synthetic, suitable for cell culture

InChI

1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1

InChI key

NGSFWBMYFKHRBD-UHFFFAOYSA-M

SMILES string

[Na+].CC(O)C([O-])=O

biological source

synthetic

product line

BioReagent

form

syrup

concentration

27-33% (enzymatic)
60 % (w/w)

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

Quality Level

200

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Application

Sodium DL-lactate solution has been used:
  • as a component in DMEM-B to prepare Dulbecco modified Eagle medium (DMEM)-C medium to evaluate the effect of medium composition on in vitro spermatogonial stem cells (SSCs) maintenance
  • as a supplement in Dulbecco′s modified Eagle′s medium-nutrient mixture F12 to obtain conditioned media of testicular macrophages
  • as a component in non-capacitation medium and TALP medium for sperm preparation and in vitro fertilization
  • in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffered synthetic oviduct fluid (SOF) media for oocyte preservation

Biochem/physiol Actions

Lactic acid is produced by lactic acid bacteria (LAB) during carbohydrate fermentation. Different microorganism synthesize different forms of lactic acid such as L(+), D(-) or DL (racemic mixture). It is preferred in food processing and preservation due to its antimicrobial property. Lactic acid is useful as a flavoring and acidifying agent.

General description

Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). Lactate is one of the main components of Ringer′s lactate or lactated Ringer′s solution.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000504245
0000504241
0000504241
0000504245
0000498505

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<BIG>Ameen SM, et al.</BIG>
Lactic Acid in the Food Industry, 20-20 (2017)
Oocyte transport: developmental competence of bovine oocytes arrested at germinal vesicle stage by cycloheximide under air
<BIG>Hashimoto S, et al.</BIG>
Journal of Reproduction and Development, 49, 61-66 (2003)
Tumour necrosis factor-alpha released by testicular macrophages induces apoptosis of germ cells in autoimmune orchitis
<BIG>Theas MS, et al.</BIG>
Human Reproduction, 23, 1865-1872 (2008)
Maintenance of mouse male germ line stem cells in vitro
<BIG>Nagano M, et al.</BIG>
Biology of Reproduction, 86, 2207-2214 (2003)
Marek Nalos et al.
Critical care (London, England), 18(2), R48-R48 (2014-03-29)
Acute heart failure (AHF) is characterized by inadequate cardiac output (CO), congestive symptoms, poor peripheral perfusion and end-organ dysfunction. Treatment often includes a combination of diuretics, oxygen, positive pressure ventilation, inotropes and vasodilators or vasopressors. Lactate is a marker of
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