L4646
Lipids Cholesterol Rich from adult bovine serum
liquid, sterile-filtered, BioReagent, suitable for cell culture, suitable for insect cell culture
Synonym(s):
Bovine Serum Lipids, Cholesterol Rich Lipids, Lipids from Bovine
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About This Item
NACRES:
NA.75
UNSPSC Code:
12352211
sterility
sterile-filtered
Quality Level
product line
BioReagent
form
liquid
composition
Cholesterol, 9.0-11.0 g/L , Protein, 15.0-25.0 g/L
technique(s)
cell culture | insect: suitable, cell culture | mammalian: suitable
impurities
Adventitious viral agents, none detected (9 CFR; 113.53), IgG, none detected (RID), Microbial content, none detected (USP XXII), Mycoplasma, none detected (Barile method), ≤6.0 EU/mg cholesterol endotoxin
storage temp.
2-8°C
General description
Cholesterol is a lipid molecule, found integrated to the cell membrane.
Application
Lipids Cholesterol Rich from adult bovine serum has been used as one of the lipid component to generate erythroblasts ex vivo. It has also been used as a standard to determine muscle cholesterol level, spectrophotometrically.
Biochem/physiol Actions
Cholesterol significantly affects the property of phospholipid membrane such as fluidity and membrane protein function. It exhibits a condensing effect towards phospholipids. Cholesterol-phospholipid interaction influences physiological properties of a lipid bilayer. Cholesterol serves as a precursor of bile acids, steroid hormones and vitamin D. Uncontrolled level of plasma cholesterol might lead to the risk of cardiovascular disorder.
Other Notes
Aqueous lipoprotein solution
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Dietary cholesterol: from physiology to cardiovascular risk
Lecerf JM and De Lorgeril M
The British Journal of Nutrition, 106(1), 6-14 (2011)
Humanized culture medium for clinical expansion of human erythroblasts
Migliaccio G, et al.
Cell Transplantation, 19(4), 453-469 (2010)
A molecular view of the cholesterol condensing effect in DOPC lipid bilayers
Alwarawrah M, et al.
The Journal of Physical Chemistry B, 114(22), 7516 -77523 (2010)