O3008

Oleic Acid-Albumin from bovine serum

Name: Oleic Acid-Albumin from bovine serum
Brand: SIGMA

liquid, sterile-filtered, BioReagent, suitable for cell culture

Synonym(s):

Oleic acid-BSA complex

Select a Size

All Photos(1)

About This Item

UNSPSC Code:

12352211

NACRES:

NA.75

MDL number:

MFCD00284022

Product Name

Oleic Acid-Albumin from bovine serum, liquid, sterile-filtered, BioReagent, suitable for cell culture

biological source

bovine

sterility

sterile-filtered

product line

BioReagent

form

liquid

composition

Oleic acid, 2 mol/mol albumin

concentration

100 mg/mL BSA in DPBS
90-120 mg/mL protein (biuret)

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

storage temp.

2-8°C

Quality Level

300

Application

Oleic Acid-Albumin from bovine serum has been used: as a component of the Dulbecco′s modified Eagle′s medium (DMEM) to study adipogenic differentiation in chicken embryonic fibroblast cell lines, to study its effects on benign prostate epithelial cells as a component of the cell culture medium to quantify triglycerides in human epithelial colorectal adenocarcinoma cells

Biochem/physiol Actions

Fatty Acid-Albumin - complexes are used as alternative sources of lipids in the development of serum-free media. Fatty acids bind to serum proteins in high proportions. Serum proteins may help in the release of beneficial fatty acids and bind those that are inhibitory. Oleic acid bound to bovine serum albumin (BSA) shows a positive effect on the growth of various cells.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response.

Yinfang Wang et al.

Journal of experimental & clinical cancer research : CR, 38(1), 147-147 (2019-04-07)

Ionizing radiation (IR) therapy is the standard first-line treatment for newly diagnosed patients with glioblastoma (GBM), the most common and malignant primary brain tumor. However, the effects of IR are limited due to the aberrant radioresistance of GBM. Transcriptome analysis

ATP7B knockout disturbs copper and lipid metabolism in Caco-2 cells.

Sarah Guttmann et al.

PloS one, 15(3), e0230025-e0230025 (2020-03-11)

Intestinal cells control delivery of lipids to the body by adsorption, storage and secretion. Copper (Cu) is an important trace element and has been shown to modulate lipid metabolism. Mutation of the liver Cu exporter ATP7B is the cause of

Pluripotent Stem Cell-Derived Hepatocytes Phenotypic Screening Reveals Small Molecules Targeting the CDK2/4-C/EBPα/DGAT2 Pathway Preventing ER-Stress Induced Lipid Accumulation.

Maddalena Parafati et al.

International journal of molecular sciences, 21(24) (2020-12-19)

Non-alcoholic fatty liver disease (NAFLD) has a large impact on global health. At the onset of disease, NAFLD is characterized by hepatic steatosis defined by the accumulation of triglycerides stored as lipid droplets. Developing therapeutics against NAFLD and progression to

ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile.

David M Favara et al.

Metabolites, 9(12) (2019-11-30)

Adhesion G Protein-Coupled Receptor L4 (ADGRL4/ELTD1) is an endothelial cell adhesion G protein-coupled receptor (aGPCR) which regulates physiological and tumour angiogenesis, providing an attractive target for anti-cancer therapeutics. To date, ADGRL4/ELTD1's full role and mechanism of function within endothelial biology

The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease.

Timothy E Thayer et al.

Scientific reports, 10(1), 9831-9831 (2020-06-21)

Non-alcoholic fatty liver disease (NAFLD) affects over 30% of adults in the United States. Bone morphogenetic protein (BMP) signaling is known to contribute to hepatic fibrosis, but the role of BMP signaling in the development of NAFLD is unclear. In

View All Related Papers

Articles

Oleic Acid in Cell Culture

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

Stearic Acid in Cell Culture

Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.